Yellow fever

Bacha, Hélio Arthur; Johanson, Gustavo Henrique

doi:10.1590/1806-9282.63.04.291

Cited by 6 publications

(6 citation statements)

References 6 publications

(5 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The last urban YF outbreak in Brazil took place in 1942 in Acre [16]; since then the risk of an urban cycle becoming established in cities such as São Paulo and Rio de Janeiro has never been as high as at present. The live-attenuated virus YF vaccine is safe, effective, and inexpensive and provides life-long immunity.…”

Section: Public Health Implications For Europementioning

confidence: 99%

Increased risk of yellow fever infections among unvaccinated European travellers due to ongoing outbreak in Brazil, July 2017 to March 2018

et al. 2018

View full text Add to dashboard Cite

Since December 2016, Brazil has faced a large outbreak of yellow fever with ca 1,500 confirmed human cases. In the first 2 months of 2018, Brazil reported almost as many cases as in 2017 as a whole. In these 2 months, five imported cases were reported among unvaccinated European travellers. Three had travelled to Ilha Grande, a popular destination among European tourists. Physicians and European travellers visiting Brazil should follow yellow fever vaccination recommendations.

show abstract

Section: Public Health Implications For Europementioning

confidence: 99%

Increased risk of yellow fever infections among unvaccinated European travellers due to ongoing outbreak in Brazil, July 2017 to March 2018

et al. 2018

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

“…22 Therefore, monitoring the occurrence of yellow fever in nonhuman primates serves as an early warning to viral circulation in a given area, which should lead to preventive vaccination of the potentially exposed human populations, as vaccination is the main preventive measure. 3,15 In Brazil, yellow fever is monitored by the Epizootics Surveillance Program of the Brazilian Ministry of Health. Each suspected case in humans or nonhuman primates must be reported immediately.…”

mentioning

confidence: 99%

Histopathologic Patterns and Susceptibility of Neotropical Primates Naturally Infected With Yellow Fever Virus

Santos

Oliveira

Lucena³

et al. 2020

Vet Pathol

View full text Add to dashboard Cite

Yellow fever is an important zoonotic viral disease that can be fatal for both human and nonhuman primates. We evaluated histopathologic changes in free-ranging neotropical primates naturally infected with yellow fever virus (YFV) compared with uninfected cohorts. The most frequent lesions in primates infected with YFV were hepatic changes characterized by midzonal necrosis with lipidosis and mild inflammation including lymphocytes, macrophages, plasma cells, and infrequently neutrophils. Importantly, severe necrotizing hepatic lesions were often observed in Alouatta sp. (howler monkeys), whereas Callithrix sp. (common marmosets) had nearly no hepatic changes. Moderate to severe hepatic necrosis was present in 21/23 (91%) of the YFV-positive Alouatta sp. compared with 10/29 (34%) of the YFV-positive Callithrix sp. ( P < .0001; odds ratio = 20). Similarly, hepatitis was more intense in Alouatta sp. compared with Callithrix sp. Furthermore, the frequency of YFV infection was significantly higher in Alouatta sp. compared with Callithrix sp. or Sapajus sp. (capuchin monkeys). Therefore, these data support the notion that Alouatta sp. is highly susceptible to infection and YFV-induced lesions, whereas Callithrix sp. is susceptible to infection but has a lower frequency of YFV-induced lesions.

show abstract

“…It is caused by an enveloped virus whose genetic material is a single-stranded RNA belonging to the Flavivirus genus of the Flaviviridae family. Its viral genome is approximately 11kb in length, which has the capacity to produce about 10 distinct proteins, 3 of which are related to structural function (capsid, pre-membrane and envelope) and 7 are classified as nonstructural (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5) The main vectors related to the proliferation of AF are hematophagous arthropods (mosquitoes) belonging to the genera Haemagogus , Sabethes and Aedes , these insects have nonhuman primates as their main food source (Monath & Vasconcelos, 2015;Bacha & Johanson, 2017.;Rollins et al, 2017;Waggoner et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and evolution of clinical cases of Yellow Fever in Brazil between the years 2007 to 2016

Fernandes

Uesugi

Silva

et al. 2022

RSD

View full text Add to dashboard Cite

Yellow Fever (YF) is a non-contagious infectious disease of variable symptoms that occurs mainly in tropical forests regions of the Americas and Africa and is caused by a Flavivirus belonging to the Flaviviridae family. Its vectors are mosquitoes of the genus Haemagogus, Sabethes and Aedes, and these have non-human primates as the main source of infection. In Brazil, there has been no record of urban AF since 1942, although the increase in cases of the wild form combined with low vaccination coverage contribute to the risk of re-urbanization of the disease Material and methods: For the study, epidemiological data were obtained from confirmed cases of Yellow Fever reported in the Notification System for Health Disorders (SINAN) available at the Informatics Department of the Unified Health System (DATASUS). Results and discussion: A total of 177 cases of were reported in Brazil, the year with the highest notification was in 2016 (52). The region with the highest occurrence of cases were the Southeast (95). Regarding the clinical evolution, of the 177 cases, 68 affected patients were cured, while 89 died from the reported injury, evidencing a high rate of lethality (50.2%). Conclusion: YF remains a public health problem, over the years there was a decrease in cases, this was due to immunization campaigns in the country, however, there was a significant increase in notifications in 2016, this whole panorama reinforces the need intensifying surveillance and expanding vaccine coverage.

show abstract

Yellow fever

Cited by 6 publications

References 6 publications

Increased risk of yellow fever infections among unvaccinated European travellers due to ongoing outbreak in Brazil, July 2017 to March 2018

Increased risk of yellow fever infections among unvaccinated European travellers due to ongoing outbreak in Brazil, July 2017 to March 2018

Histopathologic Patterns and Susceptibility of Neotropical Primates Naturally Infected With Yellow Fever Virus

Prevalence and evolution of clinical cases of Yellow Fever in Brazil between the years 2007 to 2016

Contact Info

Product

Resources

About