Seroprevalence of HCV markers among HIV infected patients from Curitiba and metropolitan region

Abstract

Results: a total of 12.9% of HIV+ patients were positive for anti-HCV antibodies, 64.1% were men and 35.9% women, with mean age of 44.5 years (24-66). The frequency of HCV among men was 16.7% and among women 9.1% (p=0.06). HCV prevalence was associated to HIV infection when compared to the general population (p<10 -6 , OR=100.4; 95CI=13.7-734.9). The parenteral route of transmission was the most frequent among coinfected patients (46.1%), and the sexual transmission among HIV+/HCV-(71.8%) (p=0.02, OR=0.2; 95CI=0.1-0.7). The frequency of intravenous drug users was higher among the coinfected patients (61.5%) compared to the non coinfected (12.6%) (p<10 -6 , OR=11.1; 95CI=4.5-27.7). Conclusion: the prevalence of coinfection with HCV in HIV+ patients is 12.9%, 88 times higher than in the general population in Curitiba. The most frequent route of transmission in the coinfected patients is parenteral, but the sexual route is also representative (34.6%).

Prevalence of HCV Infection in Newly-Diagnosed HIV Patients in the City of Belém, Pará, Brazil: A Preliminary Report

“…Our results revealed that the epidemiological profile of newly-diagnosed people with HIV/AIDS in Belém are predominantly young adults male (age between 18 and 30), single, attended the middle/high school, were selfdeclared heterosexual and non-injecting drug users. It suggests that HIV-1 epidemia in Belém is affecting younger individuals when compared to the data of 2003 and also when compared to other states of Brazil, such as Amazonas (Victoria et al, 2010) and Paraná (Tizzot et al, 2016) No association was found between seropositivity for HCV and some already known risk factors, such as history of injecting drug use or blood transfusion. Furthermore, since the single affected individual by HCV infection was 68-yearsold, there is a high chance of the HCV infection occurred prior to HIV infection.…”

Emergence of New Epidemiological Hepatitis B and C Profiles in High Risk Groups in Latin America

“…Recent studies found anti-HCV prevalence in HIV infected individuals of 1.3% in Northeast Brazil, 4.6% in Southeast Brazil, 12.9% in South Brazil, 6.9-9.7% in Midwest Brazil [16,17,[24][25][26]. In all of these studies, HCV genotype 1 was the most prevalent.…”