Zika virus

Aspectos clínicos de la infección por el virusa zika

“…Los componentes celulares del sistema inmune cutáneo son permisivos frente a la infección por zika, por lo que tendrían un rol en su entrada al organismo (4) . La entrada del virus zika a la célula hospedera está principalmente mediada por la proteína E, presente en la envoltura viral, que se une a receptores específicos y permite la fijación y fusión de la partícula viral a la célula del hués-ped.…”

Origin of the Zika virus revealed: a historical journey across the world

“…In addition to the outbreak in Micronesia, human infections with ZIKV emerged from numerous countries in sub‐Saharan Africa (1971–2010), South and Southeast Asia (1969–2013), as well as in Pacific Islands other than Micronesia and French Polynesia (2013–2014) . The second and largest ZIKV outbreak took place in French Polynesia, where it affected approximately 29000 people between October 2013 and April 2014 . Moreover, the first case of GBS associated with ZIKV was reported in November 2013 in this area …”

“…The second and largest ZIKV outbreak took place in French Polynesia, where it affected approximately 29000 people between October 2013 and April 2014 . Moreover, the first case of GBS associated with ZIKV was reported in November 2013 in this area …”

“…However, it was not until the 2015 epidemic that ZIKV captured public attention, as a result of its arrival in the Americas. In May 2015, ZIKV appeared in Brazil with the emergence of numerous reported cases of infection presumed to have been transmitted by mosquitoes or travelers . It is postulated that the virus was introduced into Brazil by participants in a world canoe race held in Rio de Janeiro, which involved athletes from four different regions of the Pacific (French Polynesia, New Caledonia, Cook Islands, and Easter Island) .…”

“…In May 2015, ZIKV appeared in Brazil with the emergence of numerous reported cases of infection presumed to have been transmitted by mosquitoes or travelers . It is postulated that the virus was introduced into Brazil by participants in a world canoe race held in Rio de Janeiro, which involved athletes from four different regions of the Pacific (French Polynesia, New Caledonia, Cook Islands, and Easter Island) . Another theory, involving viremic carriers, suggests that ZIKV was introduced by travelers attending the soccer World Cup in 2014 .…”