Assessment of serum granulysin and cathepsin-L levels in vitiligo patients
Cemre Yazar,
Atiye Akbayrak,
Zeliha Cansel Ozmen
et al.
Abstract:SUMMARY
OBJECTIVE:
Cellular and humoral immunity plays a role in the pathogenesis of vitiligo. T lymphocytes and natural killer cells involved in cellular immunity carry out their cytotoxic activities through perforin/granzyme-dependent granule exocytosis, in which granulysin and cathepsin-L are also involved. The aim of this study was to investigate the possible role of serum granulysin and cathepsin-L in the etiopathogenesis of vitiligo and their association with disease activity an… Show more
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