Comment on “Mutagenic damage among bronchiectasis patients attending in the pulmonology sector of a hospital in southern Brazil”

Response to letter to the editor: Comment on “Mutagenic damage among bronchiectasis patients attending in the pulmonology sector of a hospital in southern Brazil”

“…Regarding the content of the letter, de Moraes Malinverni et al 1 comment on the limitations of using the staining technique with eosin-methylene blue according to Leishman. This point has already been discussed elsewhere 2 , and we reinforce here that the study cited by the authors of the letter to the editor 3 did not mention staining using eosin-methylene blue according to Leishman.…”

“…Considering the points highlighted by de Moraes Malinverni et al 1 , regarding the use of “lymphocytes as a result of systemic host response,” we would like to highlight that the study was conducted in a hospital environment, including stable patients, where blood collection is not part of the routine consultations, and based on the high correlation of results obtained between oral mucosa and lymphocytes, previously described by Ceppi et al 6 , we chose to use a noninvasive method.…”