Evaluation of patients of vaccine side effects after the COVID-19 vaccine

Abstract

OBJECTIVE: Postvaccine side effects were evaluated in patients presenting to our emergency department with complaints of vaccine side effects after taking COVID-19 vaccine, and new unknown side effects ranging from mild complaints to life-threatening risks, and frequency of all side effects were investigated. This study aimed to establish a scientific resource to identify the potential side effects of the vaccine. METHODS: Patients' demographic information, clinical characteristics, epicrisis reports, COVID-19 disease and vaccination histories, vital values, and blood values were examined. The SPSS 20.0 package program was used for statistical evaluation. p<0.05 was considered statistically significant. RESULTS: Notably, 13.1% of patients presenting to the emergency department started to have complaints after taking Sinovac vaccine, whereas 86.9% of them had complaints after taking BioNTech vaccine. Also, 36.9% of patients stated that they had COVID-19. All patients had a Glasgow coma scale score of 15 during admission. No patient was hospitalized, ventilator was not needed, and all patients were discharged. While the most common presenting complaint to the emergency department after vaccination was fatigue in 29.7%, the most common diagnoses after examination in the emergency department were myalgia in 32.1% and upper respiratory tract infection in 28.6%. CONCLUSION: Results and conclusions of our study will guide healthcare workers and patients on the side effects of COVID-19 vaccine.

Evaluation of local and systemic side effects of Turkovac vaccine in adults

“…Many clinical studies have been shown that inactivated SARS-CoV-2 vaccines have a lower frequency of side effects compared to other types of vaccines [ 7 – 9 ]. Gedik MS et al reported that of the patients who attended the emergency department after vaccination, 86.9% complained after receiving the Pfizer-BioNTech vaccine (mRNA vaccine) and 13.1% after receiving the Sinovac vaccine [ 10 ]. Büyüker SM et al reported from 602 cases that complaints of physical discomfort and fever were more common in those who received the BioNtech vaccine than those who received the Sinovac vaccine.…”

Frequency And Factors Associated With Adverse Reactions After Administration of Inactivated COVID-19 Vaccine Among Health Workers

“…Upon evaluation in the emergency department, the most prevalent diagnoses were upper respiratory infection (28.6%) and myalgia (32.1%). Notably, none of the patients required ventilator support or hospitalization, and all were discharged 31 .…”

Retrospective analysis of healthcare workers admitted to emergency department due to side effects of the inactivated COVID-19 vaccine

“…Vaccination stands out as a paramount defense against viral infections [2]. Various vaccines, including mRNA, inactivated, and adenovirus vector-based, have been devised to combat COVID-19 [3]. One such vaccine, CoronaVac, an inactivated SARS-CoV-2 vaccine developed by Sinovac/Biotech, China, obtained global emergency use approval [4].…”