Relationship between contrast-induced nephropathy and long-term mortality after percutaneous coronary intervention in patients with chronic coronary total occlusion

Güzel, Tuncay; Aktan, Adem; Demir, Muhammed; Özbek, Mehmet; Aslan, Burhan

doi:10.1590/1806-9282.20220283

Cited by 9 publications

(6 citation statements)

References 26 publications

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“…On average, this population is 65 years old with a body mass index of 25.6+4.0 kg/m2 and a creatinine clearance of 60.6+27.4 ml/min. V/CrCl was 3.7+2.9 in those with CIN and 2.2+1.7 in those without (p = 0.041) [17][18][19][20].…”

Section: Resultsmentioning

confidence: 93%

Frequency of Contrast Induced Nephropathy in Diabetic Patients Undergoing Coronary Angioplasty

Khan¹,

Khan²,

Ahmad³

2022

PJMHS

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Objective: To find out the frequency of contrast induced nephropathy in diabetic patients undergoing coronary angioplasty. Material and Methods: After approval from the Hospital ethical committee, the study was conducted in the department of cardiology Hayatabad medical complex Peshawar from 28th July 2020 to 28th January 2021. A total of 136 patients were followed in this study. Oral anti-glycemic agents (metformin) were stopped before and after two days of cardiac catheterization. Previous medical record was checked including renal profile. Phlebotomist was called to take blood for random blood sugar, HbA1C level and renal functions tests (RFTs). Angioplasty was performed according to the set protocol. Serum creatinine level was checked both pre and post contrast. Results: Our study included 136 individuals, with a median age of 48 (+13.36), and we found that 59% of them were men and 41% were women. Of the 136 individuals, only 7 (5%) had contrast-induced nephropathy. Conclusion: To sum up, we found that five percent of diabetic patients having coronary angioplasty in a tertiary care hospital in Peshawar had contrast-induced nephropathy. Keywords: Diabetes mellitis, Coronary angioplasty, Contrast-induced nephropathy.

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Section: Resultsmentioning

confidence: 93%

Frequency of Contrast Induced Nephropathy in Diabetic Patients Undergoing Coronary Angioplasty

Khan¹,

Khan²,

Ahmad³

2022

PJMHS

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“…Studies have showed that elevated fibrinogen levels were associated with adverse clinical events in patients with CAD and diabetes. Besides, Güzel et al's study 41 found that diabetes was associated with mortality in patients with chronic total occlusion in the univariate cox analysis. What's more, diabetes may affect coronary collateral development.…”

Section: Discussionmentioning

confidence: 97%

Fibrinogen is Associated with Clinical Adverse Events in Patients with Psoriasis and Coronary Artery Disease

Zhao,

Zeng,

Sun

et al. 2023

JIR

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Purpose The presence of elevated fibrinogen levels is associated with cardiovascular disease. However, whether fibrinogen level is associated with adverse clinical events in patients with psoriasis and coronary artery disease (CAD) is unknown. This study aimed to investigate the relationship between fibrinogen levels and cardiovascular adverse events in these patients. Patients and Methods This retrospective cohort study collected consecutive patients with psoriasis and CAD between January 2017 and May 2022 in our hospital. The clinical records were collected, and comparisons were made between groups. The Cox regression analysis and Kaplan–Meier survival analysis were used to evaluate the association between variables. Results Of the 267 participants, one hundred and forty-seven patients (55.1%) had elevated fibrinogen levels. Compared with patients in low fibrinogen group, white blood cell and platelet counts and high-sensitivity C-reactive protein levels were higher, whereas the left ventricular ejection fraction was lower in patients in high fibrinogen group. After a median follow-up of 35.5 months, the incidence of major adverse cardiovascular events (MACEs) was higher in patients in high fibrinogen group compared with patients in low fibrinogen group (31.4% vs 16.4%, p = 0.013). The Kaplan–Meier survival curves showed the same trend (log rank p = 0.020). Subgroup analysis revealed a positive association between elevated fibrinogen levels and MACEs in patients aged <60 years (log-rank p = 0.013), those with diabetes (log-rank p = 0.027), and those who were not admitted for acute cardiovascular syndrome (log-rank p = 0.015). Conclusion Elevated fibrinogen levels were associated with adverse clinical events in patients with psoriasis and CAD, especially among patients aged <60 years, those with diabetes, and those not admitted for acute cardiovascular syndrome.

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“…All the analyzed studies had short observation periods. While various factors, including adherence issues, may affect longer-term outcomes, it is important to consider the evidence from longer-term trials [ 39 ]. Furthermore, the small sample size in each study may significantly limit the detection of secondary outcome indicators [ 40 , 41 ].…”

Section: Discussionmentioning

confidence: 99%

Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis

Qiu,

Huang,

et al. 2024

BMC Cardiovasc Disord

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Background Cardiovascular disease continues to be a leading cause of mortality worldwide, highlighting the need to explore innovative approaches to improve cardiovascular health outcomes. Time-restricted fasting (TRF) is a dietary intervention that involves limiting the time window for food consumption. It has gained attention for its potential benefits on metabolic health and weight management. This study aims to investigate the impact of TRF on key risk factors, including body weight, glucose metabolism, blood pressure, and lipid profile. Methods We conducted a systematic search in five databases (Scopus, Embase, PubMed, Cochrane, and Web of Science) for relevant studies up to January 2023. After applying inclusion criteria, 12 studies were eligible for analysis. Quality assessment was conducted using the ROB-2.0 tool and ROBINS-I. Risk of bias was mapped using Revman 5.3, and data analysis included Hartung-Knapp adjustment using R 4.2.2. Results The group that underwent the TRF intervention exhibited a significant decrease in body weight (SMD: -0.22; 95%CI: -0.41, -0.04; P < 0.05) and fat mass (SMD: -0.19; 95%CI: -0.36, -0.02; P < 0.05), while maintaining lean mass (SMD: -0.09; 95%CI: -0.08, 0.26; P > 0.05). Conclusion TRF has shown potential as a treatment strategy for reducing total body weight by targeting adipose tissue, with potential improvements in cardiometabolic function.

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Relationship between contrast-induced nephropathy and long-term mortality after percutaneous coronary intervention in patients with chronic coronary total occlusion

Cited by 9 publications

References 26 publications

Frequency of Contrast Induced Nephropathy in Diabetic Patients Undergoing Coronary Angioplasty

Frequency of Contrast Induced Nephropathy in Diabetic Patients Undergoing Coronary Angioplasty

Fibrinogen is Associated with Clinical Adverse Events in Patients with Psoriasis and Coronary Artery Disease

Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis

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