A novel predictor in patients with coronary chronic total occlusion: systemic immune-inflammation index: a single-center cross-sectional study

Demir, Muhammed; Özbek, Mehmet

doi:10.1590/1806-9282.20211097

Cited by 5 publications

(5 citation statements)

References 22 publications

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“…In the subgroups of sex, age, BMI and diabetes, there is a stable nonlinear association. SII indicators are usually used to predict the prognosis of cancer patients [13][14][15][16] and patients with CVD [17][18][19][20], and without exception, higher SII levels are associated with poor prognosis, and there has never been a nonlinear association between SII and prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…SII was calculated according to the counts of lymphocytes, neutrophils and platelets. SII usually serves as a prognostic factor for cancer patients [14][15][16] and patients with cardiovascular disease (CVD) [17][18][19][20]. Only Xu et al [21] investigated the association between various immune-inflammatory indices, including SII, and hypertension using NHANSE patients' data from 1999 to 2010.…”

Section: Introductionmentioning

confidence: 99%

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Threshold effect of systemic immune inflammatory index on hypertension in American adults (NHANES 2017–2020)

Shi,

Zhou

2023

Journal of Hypertension

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Background and aims: Research reports on the relationship between systemic immune-inflammation index (SII) and hypertension are limited. We aim to evaluate the possible relationship between SII and hypertension. Methods and results: We conducted a cross-sectional analysis of adults from the National Nutrition and Health Database from 2017 to 2020. In this study, 13 742 participants were included. The exposure variable in this study was the systemic inflammatory state as defined by SII and an outcome was hypertension. There is a nonlinear association between SII and hypertension. Two piecewise logistic regression models were used to analyze the relationship between them and calculated the cut-off point of SII to be 501.2. We found that SII on the left side of the cut-off point has nothing to do with the prevalence of hypertension. However, in patients with SII at least 501.2, the prevalence of hypertension increased with the increase of SII (odds ratio, 3.13; 95% confidence interval, 2.04–4.81). The nonlinear association between LgSII and hypertension still existed stably in the subgroups of sex, age, BMI, diabetes, and cardiovascular disease (P for interaction > 0.05). Conclusion: A cross-sectional analysis reported the threshold effect of SII on and hypertension and calculated the turning point of SII to be 501.2. Graphical Abstract, http://links.lww.com/HJH/C283

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Threshold effect of systemic immune inflammatory index on hypertension in American adults (NHANES 2017–2020)

Shi,

Zhou

2023

Journal of Hypertension

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“…Similarly, in the study with SII and CTO, the study group was different from our study. 14 The patient group selected for CTO was highly heterogeneous and included patients with ACS, stable CAD and previous bypass surgery. In addition, this study emphasized the relationship between SII and high-risk CTO rather than the relationship between CTO and SII.…”

Section: Discussionmentioning

confidence: 99%

Sistemik inflamatuar yanıt indeksin(SIRI) kronik total oklüzyon öngörülmesinde rolü: yararlı mı değil mi?

ERGÜN,

DOĞAN

2023

J Med Palliat Care / JOMPAC / jompac

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Aim: Inflammation is very important in the pathogenesis of atherosclerosis and CAD. Chronic total occlusion (CTO) is a chronic form of CAD and is common in patients with severe CAD. The aim of this study was to determine the association of the systemic inflammatory response index (SIRI), a marker of inflammation, with CTO. Materials and Methods: Our study was retrospective and included 100 CAD patients with CTO and 100 CAD patients without CTO. SIRI was compared between the two groups. Results: Among the basic clinical and laboratory characteristics of the patients, age, white blood cell, and neutrophil counts were statistically higher in the CTO group (p=0.044, p=0.044, p=0.036, respectively). SIRI parameters were similar between the groups, and no statistical difference was observed (p=0.111). According to the ROC analysis, the optimum cut-off value for SIRI was >1040 (sensitivity 70.0% and specificity 44.0%). Conclusion: SIRI is not a useful predictor for the detection of CTO.

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“…In a study, it was found that a high leukocyte count at admission was associated with high cardiovascular risk in CTO patients [11]. Demir et al found that the systemic immune-inflammatory index, which consists of many blood parameters, is closely associated with an increased risk of all-cause death in CTO patients [25]. In our study, similar to these studies, we found higher leukocyte count, CRP, and all-cause mortality in the high LGI group, and we…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of the leuko-glycemic index in coronary chronic total occlusion patients

PEKER,

ÖZBEK,

BOYRAZ

et al. 2023

The European Research Journal

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Objectives: Inflammation parameters are related to the prevalence and mortality of coronary artery disease (CAD). We aimed to evaluate the prognostic value of the leuko-glycemic index (LGI) and determine mortality in patients with chronic coronary total occlusion (CTO). Methods: A total of 546 patients were evaluated in the study. All-cause death was the primary endpoint. The leuko-glycemic index was calculated from the blood samples at admission and patients were divided into 3 groups according to their LGI levels. Kaplan-Meier survival curves were performed and logistic regression analyses was used for all multivariable analysis. Results: The mean age of the study population was 63.1 ± 11.1 years and 70.3% were male. Median follow-up time 58.2 ± 22.4 months. The mortality rate was 33.6% in the high LGI group and significantly higher compared to the other group. In multivariable analysis, LGI (OR: 1.05, 95% CI: 1,0-1.2; p = 0.02) and age (OR: 1.07, 95% CI: 1.04-1.11; p = 0.001) were found as predictors of all-cause death. Conclusions: The study revealed that high LGI is associated with all-cause death in CTO patients and LGI was a predictor of all-cause death.

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A novel predictor in patients with coronary chronic total occlusion: systemic immune-inflammation index: a single-center cross-sectional study

Cited by 5 publications

References 22 publications

Threshold effect of systemic immune inflammatory index on hypertension in American adults (NHANES 2017–2020)

Threshold effect of systemic immune inflammatory index on hypertension in American adults (NHANES 2017–2020)

Sistemik inflamatuar yanıt indeksin(SIRI) kronik total oklüzyon öngörülmesinde rolü: yararlı mı değil mi?

Prognostic value of the leuko-glycemic index in coronary chronic total occlusion patients

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