Clinical and radiological characteristics of pulmonary actinomycosis mimicking lung malignancy

Baykal, Hüsnü; ÜLGER, Ayşe Füsun; Çelik, Deniz; Tanrikulu, Fatma Benli; Tatci, Ebru

doi:10.1590/1806-9282.20211017

Cited by 1 publication

(1 citation statement)

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“…The diagnosis of pulmonary actinomycosis is quite challenging. Several reports found that 25-49% of pulmonary actinomycosis were initially suspected of lung malignancy [12]. With the development of metagenomic next generation sequencing (mNGS) technology, the detection rate of actinomyces has been increasing, but whether it is a pathogenic bacterium should be carefully considered.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary actinomycosis with polymicrobial co-infection presenting as pulmonary abscess：a case report

Song¹,

He²,

Xiong³

2023

Preprint

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Background: Pulmonary actinomycosis is very rare. It is often misdiagnosed as lung cancer, tuberculosis, pulmonary aspergillosis or pulmonary abscess. Predisposing factors are immunosuppressive conditions, poor oral hygiene and chronic lung disease. Co-infection with different strains of actinomycetes, aspergillus and bacteria is rarely reported, which is a major cause of treatment failure. Case presentation：We reported a case of 63-year old woman with 3-month history of cough, expectoration and occasional hemoptysis. Pulmonary actinomycosis with polymicrobial co-infection including actinomyces mucous, actinomyces graevenitzii, aspergillus, klebsiella pneumoniae and streptococcus constellations in left inferior lobe was confirmed by etiological culture. Combined antibiotic therapy and bronchoalveolar lavage were administrated successfully. The clinical symptoms and radiologic abnormalities had improved significantly. Conclusions:Pulmonary actinomycosis is often misdiagnosed because of the nonspecific clinical manifestations and laboratory tests.Bronchoscopy plays a key role in the diagnostic and therapeutic pathways. Co-infection make the treatment more difficult. This case improves our understanding of the diagnosis and comprehensive therapeutic strategies for pulmonary actinomycosis with polymicrobial co-infection in the elderly.

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Section: Discussionmentioning

confidence: 99%