COVID-19 and Hashimoto’s Disease

Varol, Aydan Cevik; Hatice, Uras; Görgün, Selim

doi:10.1590/1806-9282.20210242

Cited by 5 publications

(3 citation statements)

References 2 publications

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“…Subsequently, many cases of Hashimoto’s thyroiditis associated with SARS-CoV-2 infection were reported. 110 , 117 , 125 , 126 Besides, the duration taken from the initial respiratory-illness to Hashimoto’s thyroiditis outset was shown to be very similar in other cases of autoimmune complications which were shown to be consistent with the span of “cytokine storm”. 127–131 Thus, the hyperinflammatory condition is often sparked by the COVID-19 disease that possibly predisposes these infected cases to get autoimmune-related issues ( Figure 3 ).…”

Section: Sars-cov-2 Induces Subacute Thyroiditis In Post-covid-19 Patientsmentioning

confidence: 78%

“… 115 IU/mL 20 days Levothyroxine sodium (Levoid) 25 µg August, 2021 Knack et al 125 5. 36 F Fatigue Neck pain Constipation No 0.012 mIU/mL 5.26 ng/L 11.54 pg/mL 267.6 IU/mL 2.71 IU/L 276 IU/mL 10 days Levothyroxine 25 mcg once/day June, 2021 Varol et al 126 Normal range 0.3–5 mIU/mL 9–19 pmol/L 2.63–5.7 pm/L <116 IU/mL <1.75 IU/L <100 IU/mL Notes : N.A., not available; #, values are given as such from the publications. Abbreviations : M, male; F, female; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid-stimulating hormone; Anti-Tg Ab, anti-thyroglobulin antibody; Anti-TSHr-Ab, anti-thyroid stimulating hormone receptor antibody; Ab, antibody; HT, Hashimoto’s thyroiditis.…”

Section: Sars-cov-2 Induces Subacute Thyroiditis In Post-covid-19 Patientsmentioning

confidence: 99%

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SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases

Murugan¹,

Alzahrani²

2021

JIR

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Section: Sars-cov-2 Induces Subacute Thyroiditis In Post-covid-19 Patientsmentioning

confidence: 78%

Section: Sars-cov-2 Induces Subacute Thyroiditis In Post-covid-19 Patientsmentioning

confidence: 99%

SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases

Murugan¹,

Alzahrani²

2021

JIR

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“…Viral infections may trigger autoimmune diseases (1). Reports of autoimmune conditions occurring after SARS-CoV-2 infection have been described (2), including anecdotal cases of Graves' disease (3)(4)(5) and Hashimoto's thyroiditis (6,7). However, only few studies systematically evaluated the impact of COVID-19 in the development of autoimmune thyroid disease (ATD).…”

Section: Introductionmentioning

confidence: 99%

Increased prevalence of autoimmune thyroid disease after COVID-19: A single-center, prospective study

Rossini

Cassibba²,

Perticone³

et al. 2023

Front. Endocrinol.

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IntroductionThyroid dysfunctions associated with SARS-CoV-2 acute infection have been extensively described since the beginning of COVID-19 pandemics. Conversely, few data are available on the occurrence of thyroid autoimmunity after COVID-19 resolution. We assessed the prevalence of autoimmune thyroid disease (ATD) and thyroid dysfunctions in COVID-19 survivors three months after hospital admission.Design and methodsSingle-center, prospective, observational, cohort study performed at ASST Papa Giovanni XXIII Hospital, Bergamo, Italy. 599 COVID-19 survivors were prospectively evaluated for thyroid function and autoimmunity thyroperoxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb). When a positive antibody concentration was detected, thyroid ultrasound was performed. Multiple logistic regression model was used to estimate the association between autoimmunity and demographic characteristics, respiratory support, and comorbidities. Autoimmunity results were compared to a cohort of 498 controls referred to our Institution for non-thyroid diseases before the pandemic onset. A sensitivity analysis comparing 330 COVID-19 patients with 330 age and sex-matched controls was performed.ResultsUnivariate and multivariate analysis found that female sex was positively associated (OR 2.01, SE 0.48, p = 0.003), and type 2 diabetes (T2DM) was negatively associated (OR 0.36, SE 0.16, p = 0.025) with thyroid autoimmunity; hospitalization, ICU admission, respiratory support, or COVID-19 treatment were not associated with thyroid autoimmunity (p > 0.05). TPOAb prevalence was greater in COVID-19 survivors than in controls: 15.7% vs 7.7%, p = 0.002. Ultrasonographic features of thyroiditis were present in 94.9% of the evaluated patients with positive antibodies. TSH was within the normal range in 95% of patients.ConclusionsAutoimmune thyroid disease prevalence in COVID-19 survivors was doubled as compared to age and sex-matched controls, suggesting a role of SARS-CoV-2 in eliciting thyroid autoimmunity.

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Microorganisms in Pathogenesis and Management of Hashimoto Thyroiditis

Cuan-Baltazar

Soto‐Vega

2022

Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases

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COVID-19 and Hashimoto’s Disease

Cited by 5 publications

References 2 publications

SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases

SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases

Increased prevalence of autoimmune thyroid disease after COVID-19: A single-center, prospective study

Microorganisms in Pathogenesis and Management of Hashimoto Thyroiditis

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