Severe atopic dermatitis and dupilumab

Abstract

Is there an indication for the drug dupilumab in the treatment of severe atopic dermatitis? Is its constant use effective and safe? METHODS Eligibility criteriaThe eligibility criteria used to select the evidence and data were as follows: patients with severe atopic dermatitis (refractory to conventional treatment); intervention: dupilumab; comparison: placebo; outcomes: reduction of the effects of the disease and adverse events; study design: randomized clinical trials and no period and language restriction. Base consulted and strategy usedSearches were performed in the Medline database via PubMed, using the following search strategy: (Dermatitis, Atopic OR