Biomarkers in community-acquired pneumonia: can we do better by using them correctly?

Ranzani, Otávio T.; Coelho, Luís; Torres, Antoni

doi:10.1590/1806-3713/e20190189

Cited by 5 publications

(3 citation statements)

References 12 publications

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“…Los biomarcadores son sustancias que se miden objetivamente que pueden utilizarse como indicadores de un proceso fisiológico, o patológico, de una respuesta a una intervención terapéutica o de la progresión de una enfermedad [82]. Los biomarcadores de infección deben poseer características que faciliten el diagnóstico, el pronóstico y el seguimiento clínico [83]. En la neumonía, diversos estudios han evaluado el papel de los biomarcadores en el diagnóstico, la etiología, la estratificación del riesgo, la gravedad de la enfermedad, así como el inicio, la duración y la interrupción de la terapia antimicrobiana [84].…”

Section: Biomarcadoresunclassified

Community-acquired pneumonia: Epidemiology, diagnosis, prognostic severity scales, and new therapeutic options

Oliveira e Silva,

Cerqueira Batista Filho,

Pérez Flores

et al. 2023

Medwave

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This narrative review article explores the current scientific knowledge on the definition, epidemiology, diagnostic criteria, microbiology, treatment, and prevention of severe community-acquired pneumonia (SCAP) in immunocompetent adults. At present, despite major scientific advances in diagnostic evaluation, clinical management, antimicrobial therapy, and prevention, severe community-acquired pneumonia remains a major cause of morbidity and mortality, as well as having a major economic impact in terms of increased healthcare expenditure worldwide. This pathology is considered one of the leading causes of sepsis/septic shock, with an extremely high overall mortality rate, which justifies all the effort in early diagnosis, proper management, and prompt initiation of antimicrobial therapy. Including biomarkers (isolated or in combination) associated with applying diagnostic criteria and prognostic severity scales in clinical practice helps identify patients with severe community-acquired pneumonia, defines immediate admission to the intensive care unit, and, thus, minimizes the adverse outcomes of this serious pathology.

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Section: Biomarcadoresunclassified

Community-acquired pneumonia: Epidemiology, diagnosis, prognostic severity scales, and new therapeutic options

Oliveira e Silva,

Cerqueira Batista Filho,

Pérez Flores

et al. 2023

Medwave

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“…Relapse of pneumonia was initial causative organism associated with the clinical or radiological pneumonia signs post treatment (Fekih et al, 2009). CAP was responsible for most infectious disease worldwide, with advanced diagnosis and management, yet there were gaps to improve recurrence and relapse or pneumonia (Ranzani et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

COMMUNITY ACQUIRED PNEUMONIA, RISK FACTORS AND MORTALITY IN PATIENTS ADMITTED TO INTERNAL MEDICINE ICU UNIT, Al AZHAR UNIVERSITY’S HOSPITALS

Abohassan

Hashish

2021

Journal of the Egyptian Society of Parasitology

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“…Despite the prevalence of COVID-19, few studies have evaluated the risk factors on outcome in patients. In fact, many factors are used in order to predict the severity and determine the prognosis of pneumonia 6 . Early identification of risk factors for severe illness facilitated appropriate supportive care and alleviate the shortage of medical resources.…”

Section: Introductionmentioning

confidence: 99%

Abnormal Electrocardiogram and Overweight is Predictor of Outcome in COVID-19

Sun

Hou

Zhang³

et al. 2020

Preprint

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Objective: To evaluate the severe illness incidence of, predictors for, and effects on outcome by COVID-19. Methods and Results: 104 patients with COVID-19 in the Harbin Infectious Disease Hospital from Jan 15 to March 22, 2020 was retrospective include, 16.53 developed severe illness COVID-19. Patients who developed severe illness were significantly higher body-mass index (BMI), number of comorbidities, lymphocyte percentage and electrocardiogram abnormalities (P < 0.0001). Multivariate logistic regression was used to determine the predictors of developing severe illness. Independent predictors of severe illness COVID-19 were BMI and electrocardiogram abnormalities (P < 0.05). The electrocardiogram abnormalities was associated with poor outcomes (include mortality, sent to ICU or transfer to a superior hospital) (odds ratio, 7.374; 95% confidence interval, 1.365-39.846; P < 0.05). Similar results were observed in BMI. Conclusions: The higher BMI and electrocardiogram recording abnormalities on admission are the predictor of prognosis severe illness patients with the COVID-2019.

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Biomarkers in community-acquired pneumonia: can we do better by using them correctly?

Cited by 5 publications

References 12 publications

Community-acquired pneumonia: Epidemiology, diagnosis, prognostic severity scales, and new therapeutic options

Community-acquired pneumonia: Epidemiology, diagnosis, prognostic severity scales, and new therapeutic options

COMMUNITY ACQUIRED PNEUMONIA, RISK FACTORS AND MORTALITY IN PATIENTS ADMITTED TO INTERNAL MEDICINE ICU UNIT, Al AZHAR UNIVERSITY’S HOSPITALS

Abnormal Electrocardiogram and Overweight is Predictor of Outcome in COVID-19

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