Branched-Chain amino acids intake is negatively related to body adiposity in individuals at cardiometabolic risk

Abstract

Objective To assess the relationship between branched-chain amino acids intake in the current diet and the metabolic and body adiposity markers in a population at cardiovascular risk. Methods This is a cross-sectional study with 282 adults and elderly people from the Cardiovascular Health Care Program of the Universidade Federal de Viçosa. Sociodemographic, anthropometric and body composition data, as well as metabolic biomarkers were collected using standardized protocols. Dietary intake of branched amino acids was assessed using a 24-hour recall. Results Individuals with a higher branched-chain amino acids intake (≥2.6g/day, median value) had lower body fat (29.6 vs 32.2%; p=0.019), and higher serum ferritin (113.2 vs. 60.1mg/dL; p=0.006) and uric acid concentrations (4.4 vs. 4.0; p=0.023). In addition, a lower prevalence of overweight and excessive abdominal fat (p<0.05) was found in the individuals with higher branched-chain amino acids intake. They also had a higher daily intake of fiber, copper, zinc, magnesium, and iron, as well as a lower intake of total lipids. Conclusion In the present study, the intake of branched amino acids is negatively related to total and central adiposity, but more studies are needed to fully elucidate this possible relationship. (Brazilian Registry of Clinical Trials, code RBR-5n4y2g).

Bioecological Features, Biochemical and Physicochemical Parameters of Grain of New Genotypes

“…Branched chain amino acids (BCAAs), such as leucine, isoleucine, and valine, are essential for healthy functioning of cells and organs (Almeida et al, 2020). Many authors (Kihlberg & Ericson, 1964;Morey et al, 1983;Dennett et al, 2013;Tsunekawa et al, 2021) proved that high dietary intake of BCAAs prevent the prevalence of overweight and obesity in adults.…”