ObjectivesEvaluate the bleaching efficacy (BE) and tooth sensitivity (TS) of in‐office bleaching using different application tips.MethodsForty‐eight participants were selected (split‐mouth), one to receive bleaching with an attached brush tip and one with a conventional tip. The procedure was performed with Whiteness Automixx Plus 35%. The BE was evaluated at the beginning, weekly, one and 12 months post‐bleaching with a Vita Easyshade spectrophotometer (ΔE*ab, ΔE00, and WID) and with Vita classical A1‐D4 and Vita Bleachedguide shade guides units (ΔSGU). Absolute risk and intensity of TS were recorded using the Visual Analogue Scale. The equivalence of BE was analyzed using the two one‐sided t‐tests for paired samples. The absolute risk of TS was evaluated using the McNemar test, and the TS intensity was measured with the paired t test (α = 0.05).ResultsThe equivalence of BE was observed for both groups in all color evaluations (p > 0.05). A lower absolute risk and intensity of TS were observed for the attached brush tip when compared with the conventional tip (p < 0.003 and p < 0.0001).ConclusionUsing an attached brush tip showed the same BE as a conventional tip. However, for the attached brush tip, there was a reduction in TS.Clinical SignificanceThe applicator‐attached brush tip is recommended for in‐office dental bleaching, because of the possible reduction in risk and intensity of TS.