Treatment of chronic generalized periodontitis in patients with underlying hypovitaminosis D: randomized comparative clinical trial

Нестерова, О. В.; Krasilnikova, Varvara; MARGARYAN, Edita; Lazareva, Yuliya; NEMTYREVA, Liudmila

doi:10.1590/1678-7757-2022-0335

Cited by 2 publications

(1 citation statement)

References 32 publications

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“…They also concluded that a higher dose of vitamin D gives early results [ 15 ]. Nesterova et al advocated pharmaceutical intervention to correct hypovitaminosis D as part of the treatment of periodontal diseases [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Vitamin D Deficiency and Gingival Enlargement: A Case Report

Meher¹,

Goel²,

Jain³

et al. 2023

Cureus

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The occurrence of vitamin D insufficiency is rising constantly, and most pediatric patients are below the required levels. Individuals with vitamin D deficiency are more susceptible to inflammatory diseases because it reduces their immunity. The role of vitamin D deficiency in gingival enlargement has been reported in the literature. In this case report, we are describing a case in which a vitamin D supplement has resolved the gingival enlargement significantly without any invasive procedure.A 12-year-old boy reported a chief complaint of swollen gums in the upper and lower front teeth region. On clinical examination, there was minor surface plaque and calculus along with the formation of pseudopockets, but there was no clinical attachment loss. The patient has been advised to undergo laboratory tests for a complete blood profile, including a vitamin assessment. The patient reported after two and a half months with a gingivectomy on the first quadrant at a private clinic. They reported back to us because they didn't want the same trauma from surgery again and wanted a more conservative treatment option. So, on the basis of the reassessment of reports, vitamin D deficiency was confirmed, and treatment was started with 60,000 thousand I/U of vitamin D supplement weekly and advised for sunlight exposure with minimal clothing. There was a significant decrease in enlargement observed after the six-month follow-up period. Vitamin D supplements can be a more conservative treatment option for gingival enlargement of unknown etiology.

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Section: Discussionmentioning

confidence: 99%

Vitamin D Deficiency and Gingival Enlargement: A Case Report

Meher¹,

Goel²,

Jain³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

Periodontal Disease and Other Adverse Health Outcomes Share Risk Factors, including Dietary Factors and Vitamin D Status

2023

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For nearly a century, researchers have associated periodontal disease (PD) with risks of other adverse health outcomes such as cardiovascular disease, diabetes mellitus, and respiratory diseases, as well as adverse pregnancy outcomes. Those findings have led to the hypothesis that PD causes those adverse health outcomes either by increasing systemic inflammation or by the action of periodontopathic bacteria. However, experiments largely failed to support that hypothesis. Instead, the association is casual, not causal, and is due to shared underlying modifiable risk factors, including smoking, diet, obesity, low levels of physical activity, and low vitamin D status. Diabetes mellitus is also considered a risk factor for PD, whereas red and processed meat are the most important dietary risk factors for diabetes. Because PD generally develops before other adverse health outcomes, a diagnosis of PD can alert patients that they could reduce the risk of adverse health outcomes with lifestyle changes. In addition, type 2 diabetes mellitus can often be reversed rapidly by adopting an anti-inflammatory, nonhyperinsulinemic diet that emphasizes healthful, whole plant-based foods. This review describes the evidence that proinflammatory and prohyperinsulinemia diets and low vitamin D status are important risk factors for PD and other adverse health outcomes. We also make recommendations regarding dietary patterns, food groups, and serum 25-hydroxyvitamin D concentrations. Oral health professionals should routinely inform patients with PD that they could reduce their risk of severe PD as well as the risks of many other adverse health outcomes by making appropriate lifestyle changes.

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Treatment of chronic generalized periodontitis in patients with underlying hypovitaminosis D: randomized comparative clinical trial

Cited by 2 publications

References 32 publications

Vitamin D Deficiency and Gingival Enlargement: A Case Report

Vitamin D Deficiency and Gingival Enlargement: A Case Report

Periodontal Disease and Other Adverse Health Outcomes Share Risk Factors, including Dietary Factors and Vitamin D Status

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