Comparison between calcium hydroxide mixtures and mineral trioxide aggregate in primary teeth pulpotomy: a randomized controlled trial

Silva, Lidiane Lucas Costa e; Cosme‐Silva, Leopoldo; Sakai, Vivien Thiemy; Lopes, Camila Soares; Silveira, Ana Paula Pereira da; Neto, Rafael Tobias Moretti; Gomes‐Filho, João Eduardo; Oliveira, Thaís Marchini de; Moretti, Aníbal de Sant’Anna

doi:10.1590/1678-7757-2018-0030

Cited by 16 publications

(11 citation statements)

References 24 publications

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“…In accordance with the scientific literature [95], the present review confirmed that CH seemed to be the most ineffective material for pulpotomies of deciduous teeth and demonstrated the worst results when compared with all tested materials, reaching statistically significant differences at all follow-up points [52,63,69,74,81,89].…”

Section: Discussionsupporting

confidence: 89%

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Bossù

Iaculli

Giorgio

et al. 2020

JCM

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Background: Pulpotomy of primary teeth provides favorable clinical results over time; however, to date, there is still not a consensus on an ideal pulp dressing material. Therefore, the aim of the present systematic review was to compare pulpotomy agents to establish a preferred material to use. Methods: After raising a PICO question, the PRISMA guideline was adopted to carry out an electronic search through the MEDLINE database to identify comparative studies on several pulp dressing agents, published up to October 2019. Results: The search resulted in 4274 records; after exclusion, a total of 41 papers were included in the present review. Mineral trioxide aggregate (MTA), Biodentine and ferric sulphate yielded good clinical results over time and might be safely used in the pulpotomies of primary molars. Among agents, MTA seemed to be the material of choice. On the contrary, calcium hydroxide showed the worst clinical performance. Although clinically successful, formocreosol should be replaced by other materials, due to its potential cytotoxicity and carcinogenicity. Conclusion: MTA seemed to be the gold standard material in the pulpotomy of primary teeth. Promising results were also provided by calcium silicate-based cements. Further randomized clinical trials (RCTs) with adequate sample sizes and long follow-ups are encouraged to support these outcomes. deciduous or young permanent teeth with immature roots affected by caries and without evidence of radicular pathology [7,8]. Nowadays, treatment options of VPT are represented by indirect pulp treatment (namely indirect pulp capping), direct pulp capping and pulpotomy [7]. Although clinically successful in primary molars, direct capping is mainly recommended in the VPT of permanent young teeth [9,10] and indirect capping seems to possess a relative effectiveness when compared to pulpotomy procedures [11]. The latter provides favorable clinical survival rates over time and allows the vitality of primary teeth until their natural exfoliation, avoiding pulpectomy procedures [2]. Pulpotomy consists of elimination of the bacterial infection by the removal of the pulp in the pulp chamber; then, the decontaminated tooth is filled with a medicament [11]. The most frequently used agents are mineral trioxide aggregate (MTA), Biodentine (BD), formocresol (FC), ferric sulphate (FS) and calcium hydroxide (CH). When compared, FC, FS and MTA seemed to provide significantly better clinical and radiographic results as pulpotomy agents than CH after two years of follow-up; moreover, MTA showed the best performance in respect to FC and FS over time [12]. Accordingly, Stringhini et al. [13] reported that MTA yielded superior clinical and radiographical results in comparison to FC. On the other hand, electrosurgery and FS showed similar success to FC, whereas CH did not show positive evidence as medicament in pulpotomies of primary teeth [13]. In the same way, Asgary et al. [14] further stressed that MTA demonstrated better long-term outcomes in pulpotomy of primary molars when com...

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Section: Discussionsupporting

confidence: 89%

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Bossù

Iaculli

Giorgio

et al. 2020

JCM

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“…To choose a pulpotomy agent, several characteristics should be considered, such as antibacterial activity, handling process, and dentinogenesis. [25]…”

Section: Discussionmentioning

confidence: 99%

Clinical and radiographic evaluation of Allium sativum oil (garlic oil) in comparison with formocresol in primary molar pulpotomy

Kahvand

Mehran

Haghgoo

et al. 2019

J Int Soc Prevent Communit Dent

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Background: Given the side effects of formocresol as a common substance in dental pulpotomy, its substitution with a safe substance seems mandatory. Aim: To compare the clinical and radiographic success of Allium sativum oil and formocresol in the pulpotomy of the primary molars. Materials and Methods: A randomized, split-mouth, double-blind, controlled clinical trial was conducted on children with at least two asymptomatic primary molars requiring pulpotomy. A total of 90 teeth were examined in this study. They were randomly divided into two groups: the A. sativum (ALL) group ( n = 45) and the formocresol (FC) group ( n = 45). After pulpotomy, A. sativum oil was applied to the radicular pulp in the ALL groups and formocresol in the FC group. The pulp chamber was then filled with reinforced Zinc oxide Eugenol and finally restored by a stainless steel crown. Three and six months after the intervention, the teeth were evaluated by a colleague based on a modified criteria system. The results were analyzed using Wilcoxon’s test. Results: The clinical success rate was 100% in both groups after 3 and 6 months. The radiographic success rate in the ALL group and the FC group after 3 and 6 months was 82.2% and 80% and 88.9% and 84.4%, respectively. The difference between the two groups was not statistically significant ( P = 0.46). Conclusion: According to the results of this study, A. sativum oil can be used in the pulpotomy of the primary molars.

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“…Currently all sensibility tests have limitations when it comes to reliability, accuracy, and reproducibility 13 . Vitality tests are also not reliable in children due to variable patient'sresponse 14 . Assessing inflammation and presence of necrosis on histopathological sections of pulpal specimen remains the most reliable method in determining pulpal health 13 .…”

Section: Discussionmentioning

confidence: 99%

Histological Analysis of Human Pulp by Comparing Propolis, Mineral Trioxide Aggregate and Calcium Enriched Mixture as a Direct Pulp Capping Agent in Primary Molars

Rasheed¹,

Asghar²,

Sana³

et al. 2021

PJMHS

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Aim: To evaluate the histological pulp response to three direct pulp capping agents (Propolis, Mineral Trioxide Aggregate and Calcium Enriched Mixture) in primary molars. Study design: Comparative study Place and duration of study: Pediatric Dentistry department and Oral Pathology department at de’Montmorency College of Dentistry, Lahore from 1st May 2016 to 31st December 2016. Methodology: Fifty-seven human vital primary first molars were selected from patients aged 8 years. They were divided into three groups of nineteen each. Propolis, mineral trioxide aggregate (MTA) and calcium enriched mixture (CEM) were used as direct pulp capping (DPC) agents in primary molars. After pinpoint exposure, the teeth were directly pulp capped with above mentioned materials. Teeth were extracted after fifteen days for histological examination of inflammatory pulpal cell response. Results: In Propolis group (15 days duration), 15 teeth (78.9%) were in grade 1inflammation, 1 tooth (5%) was in grade 2 inflammation and 3 teeth (15.7%) were in grade 3 inflammation. In Mineral Trioxide Aggregate group 14 teeth (73.7%) were in grade 1 inflammation, 3 teeth (15.7%) were in grade 2 inflammation and 2 teeth (10.5%) were in grade 3 inflammation. In Calcium Enriched Mixture group 15 teeth (78.9%) were in grade 1 inflammation, 3 teeth (15.7%) were in grade 2 inflammation and 1 tooth (5.3%) were in grade 3 inflammation. Conclusion: The effects of Propolis, Mineral Trioxide Aggregate (MTA) and Calcium Enriched Mixture (CEM) on pulpal tissue are comparable to each other. Propolis is a cheaper material as compared to other direct pulp capping agents and easily available. Therefore, it may be used as an alternative pulp capping agent however, further investigation is required to analyze human pulpal response. Keywords: Direct pulp capping. Propolis, Mineral trioxide aggregate, Calcium enriched mixture, Primary molars

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Comparison between calcium hydroxide mixtures and mineral trioxide aggregate in primary teeth pulpotomy: a randomized controlled trial

Cited by 16 publications

References 24 publications

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Clinical and radiographic evaluation of Allium sativum oil (garlic oil) in comparison with formocresol in primary molar pulpotomy

Histological Analysis of Human Pulp by Comparing Propolis, Mineral Trioxide Aggregate and Calcium Enriched Mixture as a Direct Pulp Capping Agent in Primary Molars

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