Expression of transporter genes in anthelmintic resistant isolates of Haemonchus contortus
Janaelia Ferreira Vasconcelos Rodrigues,
Jessica Maria Leite dos Santos,
Gracielle Araújo Frota
et al.
Abstract:ATP-binding cassette (ABC) transporters, including P-glycoproteins (PGP), have been implicated in drug resistance in different organisms including
Haemonchus contortus
. This study confirmed the resistance status of
H. contortus
isolates selected for ivermectin (IVM) and oxfendazole (OXF) resistances using the fecal egg count reduction test and evaluated the gene expression of seven ABC transporters using RT-qPCR for two biological scenarios: the effect of selectio… Show more
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