In vitro antioxidant, antimutagenic and antiproliferative activities of collagen hydrolysates of jumbo squid (Dosidicus gigas) byproducts

Abstract

Hydrolysates from two different jumbo squid byproducts (fins and arms), produced by trypsin and protease type XIV were compared on the basis of their antioxidant (DPPH and ABTS radical scavenging assays), antimutagenic (Ames test) and antiproliferative (Transformation cell proliferation in M12.C3F6 murine cells) activities. Jumbo squid arms had higher content of collagen than fins, and their hydrolysates had the highest antioxidant activity. Also, jumbo squid arm-derived collagen hydrolyzed with protease XIV showed the highest antimutagenic activity. The four hydrolysates obtained showed low antiproliferative activity, however they are susceptible for further studies to be applied as food additives.

Solvent extraction effects on phytochemical constituents profiles, antioxidant and antimicrobial activities and functional group analysis of Ecballium elaterium seeds and peels fruits

“…DPPH radical scavenging activity: DPPH is a stable radical assay based on the theory that a hydrogen donor is an antioxidant, gives reducing capacity and measures compounds that are radical scavengers (Suárez-Jiménez et al, 2015). It was one of the most widely used methods for screening the antioxidant activity of vegetable materials and plant extract (Sahu et al, 2013).…”

Nutritional, phytochemical and antioxidant evaluation and FT-IR analysis of freeze dried extracts of Ecballium elaterium fruit juice from three localities

“…The scavenging ability of ABTS •+ could presumably be attributed to the presence of phytoconstituents in the fruit juices, which can act as electron donors, by reacting with free radicals, and therefore, terminate radical chain reactions (Suárez-Jiménez et al, 2015). The analysis of ABTS…”

Bioactive peptides from collagen hydrolysates from squid (Dosidicus gigas) by‐products fractionated by ultrafiltration

“…Collagen hydrolysates offer tremendous potential as new sources of bioactive peptides that display several biological properties (Samaranayaka & Li‐Chan, ). Enzymatic hydrolysates derived from squid by‐product collagen possess antioxidant, antihypertensive and anticancer properties (Aleman et al ., ; Suárez‐Jiménez et al ., ; Cuevas‐Acuña et al ., ). Furthermore, collagen hydrolysates obtained from squid by‐product have also been reported to exhibit antimutagenic activity (Suárez‐Jiménez et al ., ).…”