A comparative study on antioxidant activity of different parts of lotus (Nelumbo nuficera Gaertn) rhizome

Yang, Dongmei; Zhang, Qian; Ren, Guoping; Ying, Tiejin

doi:10.1590/1678-457x.10816

Cited by 27 publications

(31 citation statements)

References 12 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The DPPH radical scavenging activity was significantly positively correlated (p<0.001) with the total phenolic content. The results were in agreement with the previous research results from Wu et al [29] and Yang et al [30].…”

Section: Total Phenol Contentsupporting

confidence: 93%

In Vitro Anticoagulant and Antioxidant Activities of Prasaplai Recipe and Zingiber Cassumunar Roxb. Extracts

et al. 2019

View full text Add to dashboard Cite

Objective: This present study aimed to evaluate the anticoagulant activity and antioxidant properties of Prasaplai recipe (PPR), a Thai traditionalmedicine, and its major ingredient, Zingiber cassumunar (ZC) Roxb. extracts, seeking new therapeutic purposes for the recipe.Methods: Aqueous extracts of PPR and ZC Roxb. were prepared by hot water decoction technique. The anticoagulant activity of the extracts wasevaluated by prothrombin time (PT) and activated partial thromboplastin time (APTT) tests. In addition to anticoagulant activity, total phenolcontent and antioxidant activity were investigated. Total phenol content was determined using the Folin–Ciocalteu assay. The antioxidant activity wasestimated by DPPH radical scavenging activity and ferric reducing antioxidant power assay.Results: The APTT of plasma samples mixed with the PPR and ZC Roxb. extracts was significantly prolonged (p<0.05) at the concentration of1.0 mg/ml and above comparing to the control (normal saline solution) but was no significantly different for the PT. These results suggested thatPPR and ZC Roxb. extracts showed anticoagulant activity affecting the function of coagulation factor in the intrinsic pathway. All aqueous extractspossessed considerable antioxidant activity and were rich in total polyphenol.Conclusion: This finding indicates that the aqueous extracts possess significant anticoagulant and antioxidant activities, thus showing the potentialPPR and ZC Roxb. as a new source of bioactive compounds for therapeutic purposes, with particular emphasis on the prevention and treatment ofthrombosis.

show abstract

Section: Total Phenol Contentsupporting

confidence: 93%

In Vitro Anticoagulant and Antioxidant Activities of Prasaplai Recipe and Zingiber Cassumunar Roxb. Extracts

et al. 2019

View full text Add to dashboard Cite

show abstract

“…For this reason, the assay involving rubrene is useful for the characterization of 1 Δ g O 2 scavenging action in the extracts tested [14]. The test has been used for the study of photoprotective and 1 ΔO 2 scavenging actions of substances isolated from fruit and other parts of plants, as well as fruit and vegetable juices [14, 22, 24]. The rubrene method did not provide good results in the present study.…”

Section: Resultsmentioning

confidence: 87%

“…IC 50 values were lower than values for plant extracts considered antioxidant in the literature, such as Calpurnia aurea, an effective scavenger of the ABTS radical, with percentage inhibition 100 % [21]. Only samples exhibiting IC 50 < 10 μg/mL are considered very active antioxidants as they have activity comparable to the antioxidant standards quercertin, β-carotene, ascorbic acid, gallic acid and Trolox® [22]. …”

Section: Resultsmentioning

confidence: 99%

Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory

Vargas¹,

Almeida²,

Boleti³

et al. 2016

BMC Complement Altern Med

View full text Add to dashboard Cite

BackgroundThe Amazon is the largest rainforest in the world and is home to a rich biodiversity of medicinal plants. Several of these plants are used by the local population for the treatment of diseases, many of those with probable anti-inflammatory effect. The aim of the present investigation was to evaluate the in vitro antioxidant and anti-peroxidases potential of the ethanol extracts of five plants from the Brazilian Amazon (Byrsonima japurensis, Calycophyllum spruceanum, Maytenus guyanensis, Passiflora nitida and Ptychopetalum olacoides).MethodsDPPH, ABTS, superoxide anion radical, singlet oxygen and the β-carotene bleaching methods were employed for characterization of free radical scavenging activity. Also, total polyphenols were determined. Antioxidant activities were evaluated using murine fibroblast NIH3T3 cell. Inhibition of HRP and MPO were evaluated using amplex red® as susbtract.ResultsThe stem bark extracts of C. spruceanum and M. guyanensis provided the highest free radical scavenging activities. C. spruceanum exhibited IC50 = 7.5 ± 0.9, 5.0 ± 0.1, 18.2 ± 3.0 and 92.4 ± 24.8 μg/mL for DPPH•, ABTS+•, O2-• and 1O2 assays, respectively. P. olacoides and C. spruceanum extracts also inhibited free radicals formation in the cell-based assay. At a concentration of 100 μg/mL, the extracts of C. spruceanum, B. japurensis inhibited horseradish peroxidase by 62 and 50 %, respectively. C. spruceanum, M. guyanensis, B. japurensis also inhibited myeloperoxidase in 72, 67 and 56 %, respectively.ConclusionsThis work supports the folk use these species that inhibited peroxidases and exhibited significant free radical scavenging and antioxidant activities what can be related to treatment of inflammation.

show abstract

“…The extract from rhizome showed antidiabetic and antiobesity attributes. The leaf is used for diverse applications for diarrhea, high fever, hemorrhoids, leprosy stopped bleeding [22], and stopping bleeding [23]. The seed is used as a diuretic, antivomiting, anti-inflammation, and cancer [24].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Acetylcholinesterase Activity and Cytotoxicity of Different Parts of Nelumbo Nucifera Gaertn on Human Neuroblastoma Cell Line (Sh-Sy5y)

et al. 2019

View full text Add to dashboard Cite

Objective: Cognitive deterioration occurring in patients with probable Alzheimer’s disease is associated with a progressive loss of cholinergic neuronsand a consequent decline in levels of acetylcholine in the brain. This study aimed to evaluate the acetylcholinesterase (AChE) inhibitory effects andcytotoxicity in SH-SY5Y cells of different parts of three lotus extracts.Methods: AChE activity was quantified by spectrophotometry and cytotoxicity by flow 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyltetrazolium bromideassay in SH-SY5Y cells exposed to extracts.Results: All of the extracts had inhibitory effects to AChE at p<0.05, but Roseum Plenum stem extract could inhibit AChE more than 30% (p<0.05). Theall of the extracts could be an increase SH-SY5Y cell proliferation, while Album Plenum flower extract could be cytotoxic on SH-SY5Y cells.Conclusion: The extracts of lotus could be supplemented compound for cognitive deterioration or Alzheimer’s patients.

show abstract

A comparative study on antioxidant activity of different parts of lotus (Nelumbo nuficera Gaertn) rhizome

Cited by 27 publications

References 12 publications

In Vitro Anticoagulant and Antioxidant Activities of Prasaplai Recipe and Zingiber Cassumunar Roxb. Extracts

In Vitro Anticoagulant and Antioxidant Activities of Prasaplai Recipe and Zingiber Cassumunar Roxb. Extracts

Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory

Evaluation of Acetylcholinesterase Activity and Cytotoxicity of Different Parts of Nelumbo Nucifera Gaertn on Human Neuroblastoma Cell Line (Sh-Sy5y)

Contact Info

Product

Resources

About