Liquid Crystals as a Vehicle for Croton tiglium L. Oil for Deep Chemical Peel Formulations

Abstract

HIGHLIGHTS• Croton tiglium oil is a peel's active component.• Phorbol esters are present in this vegetal matrix.• Liquid crystals can encapsulate the active compounds of Croton tiglium oil.• Lamellar liquid crystalline phase at nanometric size, narrow PDI and negative zeta potential.• Liquid crystals loaded with croton oil showed suitable stability over 28 days.