Methyl Eugenol, 1,8-Cineole and Nerolidol Rich Essential Oils with their Biological Activities from three Melaleuca Species Growing in Tarai Region of North India

Abstract

The essential oils from the fresh leaves of three Melalecua spp. viz; Melaleuca leucadendron (L.) Melaleuca linariifolia Sm. and Melaleuca bracteata F. Muell. growing in Tarai region of North India were analyzed by a combination of gas chromatography/mass spectrometry. The analysis revealed the presence of several constituents of industrial and pharmacological importance. M. leucadendron essential oil was found to be dominated by E-nerolidol (85.7%) rich chemotype. 1,8-cineole (61.1%) along with significant presence of α-terpineol (12.3%), α-pinene (4.0%), β-myrcene (3.8%), and E-caryophyllene (1.7%) were identified in the essential oil from M. linariifolia Similarly M. bracteata was dominated by the presence of phenylpropanoids viz; methyl eugenol (74.8%) and methyl cinnamate (8.0%). The essential oils were studied for their in-vitro antioxidant, anti-inflammatory and antimicrobial potential. All the oils revealed potential antioxidant activity with maximum in M. bracteata essential oil. All the oils exhibited significant antibacterial activity against Bacillus megaterium, Staphylococcus aureus, Escherichia coli,Salmonella typhimurium and anti-fungal activity against phytopathogenic fungi Fusarium oxysporum, Sclerotinia sclerotiorum, Exserohilum turcicum and Curvularia lunata. The observations from present study suggest further cultivation of Melaleucas and its commercialization as industrial crops. HIGHLIGHTS E-nerolidol, 1,8-cineol and methyl eugenol rich species of Melaleuca were identified in this study. Essential oils exhibited strong antioxidant,antibacterial and Invitro anti inflammatory activity.

Chemical Composition and Biological Activities of Hedychium coccineum Buch.-Ham. ex Sm. Essential Oils from Kumaun Hills of Uttarakhand

“…The antifungal activity of HCCAO and HCCRO was significantly lower compared to standard fungicide Carbendazim (100%), even at a higher concentration (750 µL/mL) against both the tested fungi. Antifungal activity was also demonstrated for the essential oil at 50–500 µL/mL in a previous study [ 26 ].…”

Essential Oil of Lippia alba Protects Against Ischemic-Reperfusion Acute Kidney Injury

“…Studies in the literature suggest that the use of antioxidant substances can prevent or reverse the occurrence of morphological changes in models of oxidative imbalance [30]. Considering that plant extracts rich in citral and limonene have previously been shown to have antioxidant potential [31], the results obtained in this work suggest a cytoprotective potential of Lippia alba based on its antioxidant effects. Oxidative stress leads to the ROS accumulation, which is responsible to modify the cellular architecture through oxidation of membrane phospholipids, dysfunction of structural proteins, enzymes, and nucleic acids.…”

Impact of microencapsulated Ziziphora tenuior essential oil and orange fiber as natural‐functional additives on chemical and microbial qualities of cooked beef sausage

“…In addition, excellent antioxidant and antimicrobial effects of isomenthone have been reported (Alizadeh et al, 2021). Joshi et al (2022) also reported significant antimicrobial properties of 1,8‐cineole against S. aureus , E. coli , and Salmonella typhymurium .…”