Nanoemulsion Improves Babassu Palm Oil (Orbignya phalerata) Antioxidant Properties

Abstract

Background: Babassu oil is an extract from a Brazilian native coconut (Orbignya phalerata Martius) and is used both as a food and a medicinal product. Methods: we produced two babassu oil nanoemulsions and evaluated them regarding their nanoscopic stability, antioxidant activity and cytotoxicity.The nanoemulsions were characterized by Dynamic Light Scattering, and their stability was investigated for 120 days. The antioxidant activity was assessed by Spectroscopy Electron Paramagnetic Resonance, and the cytotoxicity was assessed by a colorimetric method (MTT) with the NIH/3T3 cell lineage. Results: the results showed nanoemulsions with average hydrodynamic diameter lower than 100 nm (p0.001).and a polydispersity index of less than 0.3 (p0.001), indicating monodisperse systems and good stability at room HIGHLIGHTS  Production of lipid nanoemulsions (<100 nm) of industrial interest with low energy demand. The antioxidant properties of babassu oil have been improved and the nanoemulsions are not cytotoxic. Babassu oil is a food and medicinal product.  The nanoemulsion is strategic for the developed of new antioxidants phytotherapeutics.

Bioactive compounds and benefits of by-products of Amazon babassu oil production: potential for dietary supplement, biomedical and food applications

“…researchers' attention has increasingly focused on new products and technologies based on babassu derivatives for food science and technology, biomedical and pharmaceutical applications, aiming at delivery systems for nutraceutical foods and novel therapy approaches. [16][17][18] In the last two decades, there have been reports in the literature on the significant health benefits and biological properties of babassu derivatives and nut residues for relevant applications in food additives and packaging and in the medical and pharmaceutical 19 fields: antiinflammation, 17,20,21 immunomodulation, 18,21-24 antioxidant, 13,[25][26][27][28][29] antimicrobial, 2,16,21,25,[30][31][32] anticancer, 23,33,34 antiprotozoal, 22 and antithrombotic properties, 35 and potential food supplements against dyslipidemia have all been described. 36 Furthermore, babassu mesocarp showed potential to treat leishmaniasis 24 and other infectious diseases caused by intracellular pathogens.…”

“…37 For example, babassu mesocarp is a starch-rich fraction that stands out as a bioactive and biodegradable material for active packaging applications to extend the shelf life of foods. 13,[25][26][27][28][29] The mesocarp could be a nutritious alternative to wheat flour in baking, 38 and an alternative adjuvant for developing novel vaccines and platforms against infectious diseases. 18,24 In materials engineering, babassu oil by-products (endocarp, mesocarp, epicarp, and activated carbon) were predicted to be promising adsorptive materials with potential as adsorptive species for inorganic and organic molecules.…”

Development and characterization of photoprotective nanoemulsions containing Babassu (Orbignya phalerata Mart.) lipophilic extract

“…lipophilic extract (15.0-20.0%) and oleic (12.0-18.0%) acids (Bauer et al, 2019;de Oliveira et al, 2019;Santos et al, 2021), in addition to containing small amounts of phospholipids and tocopherols (Vieira et al, 2017). These components are responsible for biological properties including antiinflammation (Reis et al, 2017;Santos et al, 2020) and healing (Fernandes et al, 2021), as well as antibacterial (Barroqueiro et al, 2016;Nobre et al, 2018), and antioxidant activities (Bauer et al, 2019;Santos et al, 2021). Thus, the BBS extract can be an important raw material for developing ecological cosmetic products.…”

“…In the last decades, nanotechnology has provided great advances, especially in the pharmaceutical and cosmetics industries, allowing the encapsulation of actives to solve problems associated with solubility and stability (Mansur et al, 2020;Santos et al, 2021;Schuenck-Rodrigues et al, 2020). In this context, oil-inwater nanoemulsions (NEs) are considered important carrier systems for lipophilic substances, including drugs, plant extracts and sunscreens (Bajerski et al, 2016;Cerqueira-Coutinho et al, 2015).…”

“…NEs are colloidal systems generally of translucent aspect, with droplet sizes varying from 10-200 nm, mainly prepared by high-energy methods (Dammak et al, 2020;Mansur et al, 2020). Lately, NEs based on BBS extract have been produced for food and some cosmetic formulations (Rocha-Filho et al, 2017;Santos et al, 2021).…”