Chemical Composition and Antioxidant Activity of Essential Oils from Populations of Baccharis dracunculifolia DC. in Southern Brazil

Abstract

Baccharis dracunculifolia DC. is a Brazilian native plant, presenting wide chemical diversity and numerous pharmaceutical and industrial applications. This research assessed the yield, antioxidant activity and the chemical similarity of essential oils from 10 populations of B. dracunculifolia in the state of Paraná, southern Brazil. The extraction of the volatile compounds was carried out by hydrodistillation, the chemical composition was determined by GC/FID and GC/MS and the antioxidant activity by the DPPH method. The essential oil yield of wild B. dracunculifolia populations ranged from 0.14 to 0.87%. The oils were predominantly composed of oxygenated sesquiterpenes (34.16 -51.01%), monoterpene hydrocarbons (18.02 -46.17%) and sesquiterpenes hydrocarbons (9.60 -17.70%). The major compounds found in all populations were β-pinene (7.65 -29.8%) and (E)-nerolidol (9.11 -21.68%). Essential oil solutions (20%) from different populations presented antioxidant capacity ranging from 27.78 to 91.67%. A negative correlation was found between the antioxidant activity and spathulenol (r = -0.696). Multivariate analyses HIGHLIGHTS  Essential oils from populations of B. dracunculifolia were investigated.  β-pinene and (E)-nerolidol were the main compounds in B. dracunculifolia populations.  The difference in the chemical profile of the essential oils is quantitative only. There is a negative correlation between the antioxidant activity and spathulenol.Tomazzoli, M.M.; et al.

Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)

“…Quintino et al (2020) verified the antimicrobial activity of the oil extracted from fresh green propolis (Figure 11), with carvacrol being the compound with the highest concentration (20.7%), finding a MIC of 6.25 μg/ml against Helicobacter pylori, 62.5 μg/ml against Mycobacterium avium and 64 μg/ml for Mycobacterium tuberculosis (Quintino et al, 2020). Tomazzoli et al (2021) analyzed the antioxidant activity of the essential oil of fresh leaves of B. dracunculifolia collected in ten locations in Paraná -Brazil. The method used was DPPH, with activity varying between 27.78% and 91.67%.…”

“… Tomazzoli et al (2021) analyzed the antioxidant activity of the essential oil of fresh leaves of B. dracunculifolia collected in ten locations in Paraná - Brazil. The method used was DPPH, with activity varying between 27.78% and 91.67%.…”

“…The oils were predominantly composed of oxygenated sesquiterpenes, monoterpene hydrocarbons, and sesquiterpene hydrocarbons. With the majority in all ten populations, β-pinene and (E)-nerolidol ( Figure 4 ) ( Tomazzoli et al, 2021 ), compounds that have already been reported with antioxidant activity ( Yu et al, 2017 ; Chen et al, 2018 ). Monteiro et al (2022) , analyzing oil from leaves of plants collected from three regions of Brazil, found that oil from the Center-West region of Brazil showed larger antioxidant activity by the DPPH methods (50.82% inhibition) and ABTS (113.63 mM TE/ml) concerning oils from the Southeast and South regions.…”

“…Research carried out with B. dracunculifolia indicates biological activities such as anti-inflammatory ( Santos et al, 2010 ; Brandenburg et al, 2020 ; França et al, 2022 ), antiulcerogenic ( Klopell et al, 2007 ; Lemos et al, 2007 ; Massignani et al, 2009 ; Costa et al, 2019 ; Boeing et al, 2021 ), immunomodulatory ( Burgos et al, 2022 ), neuroprotective ( França et al, 2022 ), antioxidant ( Veiga et al, 2017 ; Casagrande et al, 2018 ; Tomazzoli et al, 2021 ; Luchesi et al, 2022 ; Monteiro et al, 2022 ); antimicrobial ( Veiga et al, 2017 ; Casagrande et al, 2018 ; Salazar et al, 2018 ; Cazella et al, 2019 ; Pedrotti et al, 2019 ; Bonin et al, 2020 ; Timbé et al, 2021 ; Barbosa et al, 2022 ; Bernardes et al, 2022 ; Monteiro et al, 2022 ), anti-phytopathogenic ( Luchesi et al, 2022 ), insecticide and acaricide ( Chaaban et al, 2018 ; Cazella et al, 2020 ).…”

Relationship between Baccharis dracunculifolia DC. and B. microdonta DC. (Asteraceae) by Their Different Seasonal Volatile Expression

“…Furthermore, both sesquiterpene compounds are not only reported as typical components of many Baccharis essential oils (including B. dracunculifolia and B. microdonta ) [27,47,48] but also of Baccharis extracts, [49] or even identified in the volatile fraction obtained through SPME from fresh leaves of B. dracunculifolia [50] . In this study, the experimental conditions were considered enough to prevent chemical oxidations.…”