Antifungal and Antioxidant Activities of Vernonia Chalybaea Mart. ex DC. Essential Oil and their Major Constituent β-caryophyllene

Sobrinho, Antonio Carlos Nogueira; Morais, Selene Maia de; Souza, Elnatan Bezerra de; Albuquerque, Maria Rose Jane R.; Santos, Hélcio Silva dos; Cavalcante, Carolina Sidrim de Paula; Sousa, Halisson Araújo de; Fontenelle, Raquel Oliveira dos Santos

doi:10.1590/1678-4324-2020190177

Cited by 14 publications

(4 citation statements)

References 61 publications

(59 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The antioxidant activity of the EO in the present study may be related to the presence of the sesquiterpene hydrocarbon, β‐caryophyllene. A similar result was obtained by Sobrinho et al (2020), where the EO of Vernonia chalybaea , rich in β‐caryophyllene, exhibited considerable antiradical capacity. Meanwhile, other sesquiterpenes, such as elixene, cadinene, limonene, linalool, or terpinene, could also be taken into account.…”

Section: Resultssupporting

confidence: 87%

“…Monoterpenes (limonene) and sesquiterpenes (caryophyllene) were considered to be responsible for the neutralization of the DPPH radical (Mimica‐Dukic et al, 2004). Many studies have reported that the activity of an EO from plants correlated to the major components and the possible synergistic effects among them (Himed et al, 2019; Sobrinho et al, 2020; Wei & Shibamoto, 2007).…”

Section: Resultsmentioning

confidence: 99%

“…Dukic et al, 2004). Many studies have reported that the activity of an EO from plants correlated to the major components and the possible synergistic effects among them (Himed et al, 2019;Sobrinho et al, 2020;Wei & Shibamoto, 2007).…”

Section: Antioxidant Capacitymentioning

confidence: 99%

See 2 more Smart Citations

Chemical compositions and biological activities of Serevenia buxifolia essential oil leaves cultivated in Vietnam (Thua Thien Hue)

Bui

Pham

Nguyen

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

Serevenia buxifolia is an evergreen citrus plant and has attracted considerable attention due to its bioactive components and biological activities. In the present study, the essential oil (EO) from S. buxifolia cultivated in Vietnam was demonstrated to exhibit the in vitro antioxidant, thrombolytic, anti‐hemolysis, anti‐inflammatory, and antidiabetic activities. Briefly, the gas chromatography coupled to mass spectrometry analysis revealed that the leaf EO of S. buxifolia was composed of 33 components, with the main constituents being β‐carypphyllene (32.5%), and elixene (9.8%). The extracted oil possessed a fairly high free radical scavenging activity against 2, 2‐diphenyl‐1‐picrylhydrazyl (DPPH), with an IC50 value of 190.7 μg/mL compared with positive control, α‐tocopherol, IC50 value of 42.6 μg/mL. The EO also exhibited thrombolytic activity: the percentage of inhibition was found to be 70.75% at 100 μL, in comparison with 87.2% for the positive control, streptokinase. For hemolytic activity, the percentage of inhibition of the EO was from 27.4% to 59.6% at concentrations from 10 to 100 μg/mL, respectively. The results of in vitro anti‐inflammatory activity indicated that the EO of S. buxifolia leaves effectively protects the heat‐induced denaturation, with an IC50 value of 40.25 μg/mL. The EO also exhibited antidiabetic potential, with IC50 values of 87.8 and 134.9 μg/mL against α‐amylase and α‐glucosidase, respectively. It is noteworthy that the potent biological activities of the obtained S. buxifolia oil increased in a dose‐dependent manner. The results achieved show that the EO of S. buxifolia leaves can be a potential source for oxidative stress, inflammatory, and diabetic management.

show abstract

Section: Resultssupporting

confidence: 87%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Chemical compositions and biological activities of Serevenia buxifolia essential oil leaves cultivated in Vietnam (Thua Thien Hue)

Bui

Pham

Nguyen

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

show abstract

“…Entre os compostos majoritários do óleo essencial de gabiroba, o globulol apresenta atividade antioxidante pelo método DPPH• (IC50 de 5.60 mg/mL) (Rodriguez et al, 2019), assim como, o β-cariofileno que mostra potencial antioxidante pelo método DPPH• (IC50 de 0,098 mg/mL) e pelo co-oxidação β-caroteno/ácido linoleico (IC50 de 0,042 mg/mL) (Nogueira Sobrinho et al, 2020). O linalol também apresenta atividade antioxidante pelo método do DPPH• (IC50 de 0,22 mg/mL) e pelo co-oxidação β-caroteno/ácido linoleico (IC50 de 0,015 mg/mL) (Duarte, Oleastro & Domingues, 2015).…”

Section: Resultsunclassified

Potencial Antioxidante do óleo essencial de Campomanesia xanthocarpa O. Berg

Sugauara

Rickli

Scanavacca

et al. 2020

RSD

View full text Add to dashboard Cite

O objetivo do presente trabalho consistiu na determinação do potencial antioxidante do óleo essencial das folhas de Campomanesia xanthocarpa. A técnica utilizada para a extração do óleo essencial foi a hidrodestilação utilizando o aparelho de Clevenger e a identificação da composição química do óleo essencial por cromatografia em fase gasosa acoplado ao espectrômetro de massas. O potencial antioxidante foi mensurado pelos métodos de sequestro dos radicais livres do radical 2,2 difenil-1-picrilhidrazil (DPPH•), pelo sistema de co-oxidação β-caroteno/ácido linoleico e pelo método de redução do ferro (FRAP). Pela análise de cromatografia em fase gasosa acoplada à espectrometria de massas foram identificados 47 compostos, e a classe majoritária foram os sesquiterpenos hidrocarbonetos (46,80%) com os compostos majoritários biciclogermacreno (8,29%); globulol (5,67%); τ-murolol (5,59%); β-cariofileno (5,28%); germacreno D (5,03%); δ-cadineno (4,76%); τ-cadinol (4,51%) e linalol (4,17%). Os resultados encontrados para a atividade antioxidante pelo sistema de co-oxidação β-caroteno/ácido linoleico indicaram que o óleo essencial de C. xanthocarpa apresenta alto potencial antioxidante na concentração 1,00 mg/mL e potencial intermediário nas demais concentrações testadas. A atividade antioxidante do óleo essencial pelo método FRAP foi de 3,83 ± 1,99 µMol Fe+2/mg. Portanto, o óleo extraído das folhas de C. xanthocarpa apresentou potencial antioxidante pelo método de co-oxidação do beta-caroteno/ácido linoleico e FRAP, encorajando a inclusão desta espécie na lista dos antioxidantes naturais para aplicação na área de alimentos, cosmética e farmacêutica.

show abstract

Metabolite Profiling of Bioactive Compounds in Selected Species of Gomphostemma Wall. ex Benth. from the Western Ghats by GC-MS Analysis

Menon¹,

Thoppil²

2022

Springer Protocols Handbooks

View full text Add to dashboard Cite

Antifungal and Antioxidant Activities of Vernonia Chalybaea Mart. ex DC. Essential Oil and their Major Constituent β-caryophyllene

Cited by 14 publications

References 61 publications

Chemical compositions and biological activities of Serevenia buxifolia essential oil leaves cultivated in Vietnam (Thua Thien Hue)

Chemical compositions and biological activities of Serevenia buxifolia essential oil leaves cultivated in Vietnam (Thua Thien Hue)

Potencial Antioxidante do óleo essencial de Campomanesia xanthocarpa O. Berg

Metabolite Profiling of Bioactive Compounds in Selected Species of Gomphostemma Wall. ex Benth. from the Western Ghats by GC-MS Analysis

Contact Info

Product

Resources

About