Linfoma mediastinal em equino - relato de caso

Abstract

RESUMOUma égua SRD, com 20 anos de idade, foi encaminhada ao hospital veterinário com histórico de emagrecimento, perda de apetite e aumento de volume na região peitoral e no pescoço. Aos exames físico e laboratorial, constatou-se que o animal apresentava taquicardia, taquipneia, hiperproteinemia, hiperfibrinogenemia e hipoalbuminemia. À auscultação cardíaca, os sons das válvulas pulmonar e aórtica não foram audíveis. Realizaram-se as avaliações eletrocardiográfica e ecodopplercardiográfica transtorácica bilateral, nas quais se observaram presença de efusão pleural e deslocamento caudal do coração. Na varredura ultrassonográfica ao redor do coração, constatou-se a presença de uma massa na base do coração. Para tentar amenizar o quadro respiratório, foi realizada drenagem torácica. A efusão pleural apresentava característica serossanguinolenta, com padrão citológico inflamatório. Algumas horas após retornar a baia, o animal veio a óbito. Realizou-se a necropsia, na qual pôde ser observada a presença da massa posicionada ao redor do tronco braquiocefálico. Na análise histopatológica, diagnosticou-se o linfoma difuso de células pequenas e médias.

Linfoma multicêntrico de Células T em uma potra Crioula

“…An antibiotic therapy was provided, which showed no response, thus resulting in the suspension of therapy and rejection of this clinical suspicion. Cases of multicentric lymphoma with a history of respiratory signs similar to this case have been reported (Campos et al, 2014;Gravena et al, 2018). Therefore, neoplasm should be considered in the differential diagnosis of cases presenting with similar clinical signs.…”

“…Hematological examination during hospitalization revealed anemia, thrombocytopenia, neutropenia, and hyperfibrinogenemia, which are often reported in cases of equine lymphosarcoma (Meyer et al, 2006;Gravena et al, 2018). Animals with lymphoma typically develop unresponsive anemia, as described by Meyer et al (2006).…”

“…Lymphomas are heterogeneous hematopoietic neoplasms, with various clinical presentations and laboratory and morphological changes (Meyer, Delay, & Bienzle, 2006;Gravena et al, 2018). Lymphomas are uncommon in horses and have no sex, race, or age predilections (Meyer et al, 2006).…”

“…Lymphomas are uncommon in horses and have no sex, race, or age predilections (Meyer et al, 2006). Their clinicopathological presentations in different domestic species have been classified into thymic, alimentary, multicentric, cutaneous (Gravena et al, 2018) and solitary extragonadal forms (Taintor & Schleis, 2011).…”

“…Clinical symptoms observed in the initial developmental phase of lymphomas are nonspecific, such as lethargy, weight loss, and depression, and its definitive diagnosis requires histopathological examination (Taintor & Schleis, 2011). Further, the prognostication tends to be delayed (Gravena et al, 2018). In such cases, the laboratory findings vary, although they present with hematologic evidence of the disease, such as unresponsive anemia, thrombocytopenia, leukopenia, and hyperfibrinogenemia (Meyer et al, 2006).…”