Emergence of multidrug-resistant bacteria isolated from surgical site infection in dogs and cats

Abstract

Surgical site infections (SSIs) and antimicrobial resistance among pathogens causing SSI are a growing concern in veterinary hospitals. One major reason, the widespread use of antimicrobials, has led to increased incidence of SSIs. This study identified bacteria and resistance profiles to antimicrobials in the SSI cases diagnosed at the Surgical Clinic of Small Animals in the Veterinary Hospital, Federal University of Viçosa, Brazil. The main genus identified was Staphylococcus, followed by Escherichia, Enterococcus, Bacillus, Shigella, Citrobacter, Proteus, Morganella, Serratia, Enterobacter, Pseudomonas and Klebsiella were also found, but in small number. The results indicated the predominance of Gram-negative bacteria among the collected samples. Most of isolates identified were resistant to more than one of the following antimicrobials: ampicillin, tetracycline, enrofloxacin, amoxicillin/clavulanic acid and cephalotin. Of the 17 Staphylococcus sp. isolates, two (11.8%) were methicillin-resistant Staphylococcus aureus (MRSA) and 11 (64.7%) of them were methicillin-resistant Staphylococcus pseudintermedius (MRSP). There were bacterial genera identified with resistance to all tested antimicrobials in different proportions. This should alert veterinary hospitals to the emergence of multidrug-resistant bacteria and to the requirement for the revision of surgical protocols with regard to antimicrobial prophylaxis and therapy.

Infecção Do Sítio Cirúrgico Por Microrganismos Patogênicos Na Clínica Cirúrgica De Pequenos Animais

“…De acordo com Corsini et al (2020), os principais agentes etiológicos infecciosos de ISC são os gêneros Staphylococcus, seguido por Escherichia, Enterococcus, Bacillus, Shigella, Citrobacter, Proteus, Morganella, Serratia, Enterobacter, Pseudomonas e Klebsiella também detectados em uma menor frequência. Além desses microrganismos patogênicos, ainda foram relatados aqui no Brasil, os gêneros Streptococcus e Acinetobacter (ARIAS et al, 2013).…”

Titanium Dioxide Nano-Formulation: Characterization, Antimicrobial Activity, and Wound Healing in Animals

“…The overall healing score for each group was calculated by summing the individual criterion scores. Lower scores indicated poor healing status (8)(9)(10)(11), while middle (12)(13)(14)(15) and good (16)(17)(18)(19) scores indicated intermediate and good healing status, respectively.…”

“…Generally, broad spectrum antibiotics and antiseptics are frequently used in wound management due to their cost-effectiveness and efficacy [5,6]. The extensive use of broad-spectrum antibiotics is a major contributor to the emergence of resistant bacteria and multidrug-resistant bacteria (MDR) on wound sites [7,8]. Furthermore, they are regarded as reservoirs for the transmission of resistant bacteria to humans through close contact [9,10].…”