Associations between new and old anthropometric indices with type 2 diabetes mellitus and risk of metabolic complications: a cross-sectional analytical study

Abstract

Background Obesity can increase the risk of diabetes mellitus and complications associated with it. Objectives The aim of this study was to estimate the associations between new and old anthropometric indices and the risk of type 2 diabetes mellitus (T2DM) and its metabolic complications. Methods In this cross-sectional analytical study, 110 T2DM subjects and 110 healthy controls were selected by convenience sampling. Metabolic factors were evaluated including the atherogenic index of plasma (AIP), glycemic status, lipid profile, blood pressure, kidney indices, new anthropometric indices (abdominal volume index [AVI], body shape index [ABSI], lipid accumulation product [LAP], body adiposity index [BAI], and conicity index [CI]), and old anthropometric indices (weight, body mass index [BMI], and waist and hip circumference [WC and HC]). Results Significant positive correlations were observed between AVI, LAP, and BAI and fasting blood glucose and HbA1c in the T2DM group (p < 0.001 for all associations). The odds ratio (OR) for T2DM elevated significantly with increasing BMI (OR: 1.30, 95% CI: 1.20-1.42), LAP (OR: 1.20, 95% CI: 1.13-1.27), and BAI (OR: 1.32, 95% CI: 1.21-1.43). The indices AVI (OR: 1.90, 95% CI: 1.57-2.29), LAP (OR: 1.19, 95% CI: 1.13-1.27), BAI (OR: 1.19, 95% CI: 1.12-1.26), WC (OR: 1.29, 95% CI: 1.18, 1.42), and HC (OR: 1.07, 95% CI: 1.01, 1.14) significantly increased the risk of metabolic syndrome (MetS). Conclusions Associations were identified between obesity indices and diabetes. These indices could be used in clinical practice for evaluation and control of T2DM.

Factors correlated with targeted prevention for prediabetes classified by impaired fasting glucose, impaired glucose tolerance, and elevated HbA1c: A population-based longitudinal study

“…Our study presented that RFM showed stronger correlation than WC, WHtR, WHR, and BMI for prediabetes but failed to detected association with the elevated HbA1c. Previous studies suggested that significant positive correlations were observed between AVI, LAP, BRI, BAE, and DM ( 53 – 56 ), but few studies have focused on the Chinese population and prediabetes. BAE showed the strongest correlation than other indicators for total prediabetes in our study.…”

Data mining approaches for type 2 diabetes mellitus prediction using anthropometric measurements

“…Type 2 diabetes mellitus (T2DM) is a chronic disease that is diagnosed by an abnormal blood glucose level due to insulin deficiency or insulin resistance 1 . However, recent studies suggest that the accumulation of ectopic lipids may play an important role in developing T2DM 2 .…”

“…Type 2 diabetes mellitus (T2DM) is a chronic disease that is diagnosed by an abnormal blood glucose level due to insulin deficiency or insulin resistance. 1 However, recent studies suggest that the accumulation of ectopic lipids may play an important role in developing T2DM. 2 The International Diabetes Federation reports that the global prevalence of diabetes in adults in 2021 was 536.6 million people, and it is estimated that it will rise to 783.2 million in 2045.…”

Comparação entre variáveis categóricas em estudos clínicos e experimentais

“…In clinical-epidemiological research, it is highly usual to present an initial descriptive table containing demographic data on subgroups, in order to demonstrate their homogeneity. For example, Amiri et al 17 included 110 cases and 110 controls in a cross-sectional study to test associations between anthropometric indices and type 2 diabetes mellitus. Of these diabetic patients, 75 (51%) were female, whereas there were only 72 women (49%) in the control group.…”

“…Na pesquisa clínico-epidemiológica, é bastante usual que se apresente uma tabela inicial descritiva com os dados demográficos dos subgrupos, a fim de atestar a sua homogeneidade. Por exemplo, Amiri et al 17 incluíram 110 casos e 110 controles em um estudo transversal para testar a associação de índices antropométricos e diabetes melito tipo 2. Entre os diabéticos, 75 (51%) eram do sexo feminino, enquanto no grupo controle foram encontradas 72 mulheres (49%).…”