Escleroterapia com espuma de polidocanol em veias safenas magnas e suas tributárias bilateralmente em tempo único

Miranda, Luiz Antonio; Carmo, Rachel Cristina do; Sathler-Melo, Claudia Carvalho; Santos, Guilherme de Castro

doi:10.1590/1677-5449.200178

Cited by 2 publications

(3 citation statements)

References 27 publications

(67 reference statements)

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“…After screening the titles and abstracts for eligibility, we retrieved 38 articles, of which 28 were subsequently included. 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 The screening process is summarized in Figure 1 . An overview of the included articles is provided in Table 1 .…”

Section: Resultsmentioning

confidence: 99%

Migraine aura‐like episodes following sclerotherapy for varicose veins of the lower extremities—A systematic review

et al. 2023

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Objective: This systematic review provides a summary and evaluation of cases of migraine aura-like episodes elicited by sclerotherapy of veins of the lower extremities and discusses possible underlying mechanisms.Background: Sclerotherapy is a commonly used treatment for varicose veins.Symptoms resembling migraine aura have been reported during and following sclerotherapy of the lower extremities, suggesting that sclerotherapy may elicit migraine aura. Methods:We searched PubMed for articles reporting neurological complications that were transient and fully reversible following sclerotherapy treatment for varicose veins in the lower limbs. There were no restrictions regarding article language or publication date. Only original studies and case reports were included. Two authors independently reviewed included articles in detail. Data were extracted from each article, including details on symptoms, previous migraine history, sclerotherapy method, and the presence of a right-to-left cardiac shunt in patients. We evaluated whether episodes fulfilled modified International Classification of Headache Disorders, 3rd edition, criteria for 1.2 Migraine with aura or 1.5.2 Probable migraine with aura. Results:The search yielded 777 articles, 28 of which were included. Twenty-six articles reported 119 episodes of transient neurological symptoms in 34,500 sclerotherapy sessions. Two additional articles reported six episodes of transient neurological symptoms with no specification of the number of sessions. Of the 125 episodes, 119 involved transient visual disturbances, and eight met the modified criteria for Probable migraine with aura. In most episodes (98%), clinical information was insufficient to determine if the criteria were fulfilled.Conclusions: Symptoms that are clinically indistinguishable from migraine with aura attacks may occur following sclerotherapy, although this likely is rare. Microembolization through a right-to-left shunt triggering cortical spreading depolarization is a possible mechanism. Our findings are limited by infrequent specific assessments for

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Section: Resultsmentioning

confidence: 99%

Migraine aura‐like episodes following sclerotherapy for varicose veins of the lower extremities—A systematic review

et al. 2023

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“…This, combined with their increased surface area, optimizes agent contact with the vascular endothelium and maximizes the sclerosant effect. 5,[7][8][9] Liquid sclerosants can be modified to foams by off-label physician conversion, most commonly by the double syringe system or the Tessari Method. [10][11][12] A liquid preparation of polidocanol is distributed as the drug Asclera (Merz North America, Inc., Raleigh, NC) in the United States.…”

Section: Formulationsmentioning

confidence: 99%

“…This, combined with their increased surface area, optimizes agent contact with the vascular endothelium and maximizes the sclerosant effect. 5,7–9 Liquid sclerosants can be modified to foams by off-label physician conversion, most commonly by the double syringe system or the Tessari Method. 10–12…”

Section: Formulationsmentioning

confidence: 99%

Polidocanol: A Review of Off-Label Dermatologic Uses

Nguyen

Stender

Bur

et al. 2022

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BACKGROUND Polidocanol is an FDA-approved treatment of incompetent great saphenous veins, accessory saphenous veins, and visible varicosities of the great saphenous vein system, but numerous other off-label dermatological applications have been reported. OBJECTIVE To describe the various off-label dermatological clinical uses of polidocanol, as well as efficacy and adverse effects. METHODS The review of studies searchable on PubMed from 2004 to 2021 describing clinical uses of polidocanol to determine efficacy and adverse effects associated with various dermatologic applications. RESULTS Polidocanol has shown efficacy in the treatment of mucocele of minor salivary gland, hemangioma, upper extremity veins, reticular veins of the chest, facial veins, pyogenic granuloma, lymphangioma circumscriptum, digital mucous cyst, mixed skin ulcers, cutaneous focal mucinosis, seromas, glomuvenous malformations, acne cysts, lymphocele, and dissecting cellulitis. Commonly reported side effects include pain, erythema, swelling, ecchymosis, and ulceration. Most sources were case reports and small prospective studies, as such the strength of data supporting many uses is limited by small sample sizes and lack of controls. CONCLUSION Although polidocanol is currently only FDA approved for incompetent great saphenous veins, accessory saphenous veins, and visible varicosities of the great saphenous vein system, the use of polidocanol has been selected for a variety of off-label clinical applications.

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Escleroterapia com espuma de polidocanol em veias safenas magnas e suas tributárias bilateralmente em tempo único

Cited by 2 publications

References 27 publications

Migraine aura‐like episodes following sclerotherapy for varicose veins of the lower extremities—A systematic review

Migraine aura‐like episodes following sclerotherapy for varicose veins of the lower extremities—A systematic review

Polidocanol: A Review of Off-Label Dermatologic Uses

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