Photodynamic therapy in cancer treatment: properties and applications in nanoparticles

Abstract

Most of the treatment strategies for tumors and other disorders is photodynamic therapy (PDT). For several years, increasing the efficiency of nanostructured treatment devices, including light therapy, has been considered in different treatment methods. Light Dynamics The use of nanomaterial in this method's production and progress. The use of nanoparticles as carriers is a promising accomplishment, since all the criteria for an ideal photodynamic therapy agent can be given with these nanomaterials. The kinds of nanoparticles that have recently been used in photodynamic therapy are mentioned in this article. Latest advancements are being explored in the use of inorganic nanoparticles and biodegradable polymer-based nanomaterial as carriers of photosynthetic agents. Photosynthetic nanoparticles, self-propagating nanoparticles, and conversion nanoparticles are among the successful photodynamic therapy nanoparticles addressed in this report.

Bacterial outer membrane vesicles as drug delivery carrier for photodynamic anticancer therapy

“…With the introduction of nanomaterials in PDT, based on their feature of the nanoscale structure, variable morphology, low biological toxicity, good biocompatibility, and easy modification, leading different types of nanoparticles as drug carriers of PSs provided more possibilities to overcome defects of PDT ( Younus et al, 2023 ). For example, up-conversion nanoparticles (UCNPs) and persistent luminescence nanoparticles (PLNPs) can be used as drug delivery carriers to overcome the poor penetration depth of excitation light sources ( Qiu et al, 2018 ; Fritzen et al, 2020 ).…”