Antibacterial and antifungal activity of methanolic extracts of Salix alba L. against various disease causing pathogens

Abstract

The present study was aimed to manifest the antibacterial and antifungal activity of methanolic extracts of Salix alba L. against seven Gram-positive and Gram-negative bacterial pathogens e.g. Streptococcus pyogenes, Staphylococcus aureus (1), S. aureus (2), Shigella sonnei, Escherichia coli (1), E. coli (2) and Neisseria gonorrhoeae and three fungal isolates from the air such as Aspergillus terreus, A. ornatus, and Rhizopus stolonifer. Two different serotypes of S. aureus and E. coli were used. The agar well-diffusion method results showed the dose-dependent response of plant extracts against bacterial and fungal strains while some organisms were found resistant e.g. E. coli (1), S. sonnei, A. terreus and R. stolonifer. The highest antibacterial activity was recorded at 17.000±1.732 mm from 100 mg/mL of leaves methanolic extracts against S. pyogenes while the activity of most of the pathogens decreased after 24 h of incubation. The highest antifungal activity was reported at 11.833±1.0 mm against A. ornatus at 50 mg/mL after 48 h of the incubation period. These experimental findings endorse the use of S. alba in ethnopharmacological formulations and suggest the use of methanolic extracts of the said plant to develop drugs to control the proliferation of resistant disease causing pathogenic microbes.

Willow Bark-Derived Material with Antibacterial and Antibiofilm Properties for Potential Wound Dressing Applications

“…We previously observed growth inhibition of several bacterial species, including S. aureus, on willow bark samples, e.g., for water extracts from the bark of 16 Salix clones and methanolic extracts from stem bark and leaves of Salix alba . These effects have been mainly attributed to salicinoids and various polyphenols.…”

“…We previously observed growth inhibition of several bacterial species, including S. aureus, on willow bark samples, e.g., for water extracts from the bark of 16 Salix clones 48 and methanolic extracts from stem bark and leaves of Salix alba. 49 These effects have been mainly attributed to salicinoids and various polyphenols. However, these compounds were depleted from WBFBs during their manufacturing process, and nevertheless, they retained strong antibacterial activity.…”

Chemical Profile and Biological Effects of an Herbal Mixture for the Development of an Oil-in-Water Cream

“…Previous studies pointed out antibacterial potential for distinct products derived from K. lappacea [ 21 ], H. virginiana [ 19 ], and S. alba [ 22 ]. Specifically, the H. virginiana extract proved to have an antiinflammatory and antibacterial effect on Cutibacterium acnes -induced inflammation in acne, whereas K. lappacea and S. alba showed important antibacterial activities toward a large number of bacterial strains, such as Streptococcus pyogenes, Staphylococcus aureus, S. epidermidis, and Escherichia coli .…”

A Comparative Analysis of Phytochemicals, Metal Ions, Volatile Metabolites in Heart Wood, Stem Bark and Leaves of Salix alba L. along with in Vitro Antioxidant, Antacid, Antimicrobial Activities for Sake of Environment Conservation by Substitution of Stem Bark With Leaf

“…In other report, a 100 mg/mL methanolic extract of SA-L has shown prominent inhibition against S. pyogenes bacterial strain, and poor inhibitions were found against Staphylococcus aureus, and Escherichia coli. [24] This is the first comprehensive study on SA where all aspects have been covered w. r. t. HPLC, metal ions analysis, GC-MS/MS study, TPC, TFC, antimicrobial, antioxidant activities. There is no report on the metal ions analysis, antacid, prebiotic activities, and simultaneous HPLC of three major markers in single run of SA and its various parts (SA-L, SA-HW, and SA-SB).…”