The Effect of Physical Exercise on Blood Sugar Control in Diabetic Patients

Wei-lin, Wang; Huang, Meng-Chun; Wang, Junrong

doi:10.1590/1517-8692202127032021_0103

Cited by 5 publications

(2 citation statements)

References 9 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thermal cycling was performed as described on the Applied Biosystems (21) sequence detection system. Pfafl method (2 -ΔΔCt , ΔΔCt = ΔC t Sample - ΔC t Control ) was used to determine the fold change of each gene expression (22). The primers used to assess the expression of Bax, Bcl-2, and GAPDH (as an internal control) genes possessed the following sequences (14):…”

Section: Methodsmentioning

confidence: 99%

Effect of crocin and treadmill exercise on oxidative stress and heart damage in diabetic rats

Pourmousavi¹,

Asadi²,

Zehsaz³

et al. 2023

Preprint

View full text Add to dashboard Cite

Objective: In diabetes the production of free radicals and inflammatory agents in the heart tissue is increased and the expression of genes associated with the induction of apoptosis is altered. Considering the importance of common cardiovascular disorders in diabetes, this study investigated the effect of eight weeks of aerobic exercise and kerosene use alone, as well as tissue damage and oxidative stress caused by diabetes in the heart of adult rats. Materials and Methods: To induce diabetes, streptozotocin 50 mg/kg was injected as a single dose intraperitoneally. After 72 hours, blood glucose levels were monitored by a glucometer, and blood glucose above 250 mg/dl was considered diabetes. Continuous treadmill exercise was performed for eight weeks by placing the animal on the treadmill. Next, the animals were anesthetized, and samples were taken from the hearts and frozen in liquid nitrogen. Then, superoxide dismutase (SOD), glutathione peroxidase (GPx), and malondialdehyde (MDA) were measured in the cardiac tissue. Finally, the hearts of half of the animals were immediately immersed in formalin solution for histological changes. Results: According to our findings, diabetes increased lipid peroxidation, which was characterized by increased MDA levels in the control diabetes group and decreased SOD and GPx levels (P <0.05). It also changes the balance of expression of genes associated with apoptosis control, increased Bcl-2-associated X (Bax) expression, and decreased Bcl-2 expression (P <0.05). Also, we observed the induction of apoptosis in cardiac tissue. Using eight weeks of continuous exercise and administration of crocin significantly reduced blood sugar levels and lipid peroxidation and increased the activity of antioxidant enzymes and Bcl-2 gene expression compared to the diabetes control group. In addition, continuous exercise and kerosene improved the oxidative stress parameters in the control group. Conclusions: The results of this study showed that diabetes could cause oxidative stress and heart dysfunction. Moreover, simultaneously and separately, aerobic exercise with treadmill and crocin administration can reduce these disorders and prevent apoptosis in the heart tissue.

show abstract

Section: Methodsmentioning

confidence: 99%

Effect of crocin and treadmill exercise on oxidative stress and heart damage in diabetic rats

Pourmousavi¹,

Asadi²,

Zehsaz³

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Therefore, if walking, dietary regulation, and education about managing diabetes-related complications are carried out regularly, diabetes complications such as heart problems and hypertension will be more easily prevented to reduce diabetes and difficulties in the elderly. However, a gap in previous research is a lack of knowledge about the effect of regular walking exercise, which includes a walking exercise program (Wang et al, 2021;Karstoft et al, 2013;Sung & Bae, 2012). This study aimed to determine the effect of walking exercise on blood pressure and blood sugar in the elderly.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Walking Exercise on Blood Pressure and Blood Glucose in the Elderly

Rizka

Ambardini

Virama

et al. 2022

IJKSS

View full text Add to dashboard Cite

Background: Walking exercise is a physical activity that stimulates various components of physical fitness. Particularly in the elderly, it improves blood circulation, strengthens bones, lowers blood pressure and glucose. Objective: This study aimed to determine the effect of walking exercise on blood pressure and blood glucose in the elderly. Method: This research was experimental research that used a quantitative approach. Participants were elderly aged 60 years with a history of hypertension and high blood glucose. The samples in this study were 34 people who were determined based on a simple random sampling technique. The experimental group was given physical activity treatment for walking 3x a week with mild to moderate intensity for 60 minutes for three weeks. The control group did not participate in any treatment. The walking program took place outside on a 1 mile/1,609 meter track. Before beginning the exercise program, participants should warm up for 5-10 minutes with a leisurely walk. In this case, the participant’s mileage is 1 mile. The instrument used to measure blood pressure in this study was an aneroid sphygmomanometer, while a glucometer was used to measure blood glucose levels. Results: This study found that: Based on the Mann-Whitney test, it showed that there was a significant effect of walking exercise on decreasing systolic blood pressure (p 0.005), diastolic blood pressure (p 0.018), and reducing blood sugar (p 0.031). Conclusion: Walking exercise has a significant effect on blood pressure and blood glucose in the elderly.

show abstract