Mental health interventions following COVID-19 and other coronavirus infections: a systematic review of current recommendations and meta-analysis of randomized controlled trials

Damiano, Rodolfo Furlan; Santi, Talita Di; Beach, Scott R.; Pan, Pedro Mário; Lucchetti, Alessandra Lamas Granero; Smith, Felicia A.; Forlenza, Orestes Vicente; Fricchione, Gregory L.; Miguel, Eurí­pedes Constantino; Lucchetti, Giancarlo

doi:10.1590/1516-4446-2020-1582

Cited by 22 publications

(26 citation statements)

References 173 publications

(225 reference statements)

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“…Obstetricians and other healthcare professionals must closely monitor the mental health of pregnant women in this era of COVID-19 in Saudi Arabia and worldwide. Previous studies found that mental health interventions and support programs have improved mental health of the participants during medical crises [28][29][30]. Psychological, psychiatric, education and other interventions either in person or online have improved the mental health of individuals during COVID-19, Ebola, and SARS pandemics [29][30][31].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 related psychological distress and fears among mothers and pregnant women in Saudi Arabia

et al. 2021

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Objectives This study objectives were to investigate maternal psychological distress, mothers’ fear of their children contracting COVID-19, mothers’ perceptions of the information available regarding children and COVID-19, changes in children’s behavior during lockdown, and concerns of pregnant women in Saudi Arabia. Methods This cross-sectional study surveyed women aged 18 years and older who either had children under 10 years of age or were pregnant at the time of the survey. The outcomes included psychological distress, mothers’ fear of their children contracting COVID-19, change in children’s behaviors during COVID-19 lockdown and pregnant women’s concerns. Multivariable ordinary least squares regression models were employed to examine the adjusted associations between sociodemographic factors and psychological distress, as well as fear of COVID-19. Results Of 628 women, 11.8% (n = 74) were pregnant at the time of survey. Most of the pregnant women (89.2%, n = 66) had some degree of concerns about their unborn babies getting infected during delivery in the hospital. Among mothers of children under 10 years of age (n = 564), half (n = 282) reported change in their children’s behavior during the lockdown. Most mothers and pregnant women (94.9%, n = 569) had some degree of psychological distress. Mothers and pregnant women with a college degree had significantly lower psychological distress (β = -1.346; p = 0.014) than women with a high school education or less. Similarly, mothers and pregnant women with monthly family income ≥ US$ 1,333 had lower psychological distress than those with < US$ 1,333. Women with pre-existing chronic physical (β = 2.424; p < 0.001) or mental (β = 4.733; p < 0.001) conditions had higher psychological distress than those without these conditions. Having children in the house was a contributory factor for higher psychological distress. For example, mothers with one child (β = 2.602; p = 0.007) had significantly higher psychological distress compared to expectant mothers without children in the house. Conclusions Most mothers and expectant mothers in our study had moderate to high levels of psychological distress during the COVID-19 pandemic outbreak in Saudi Arabia. Education, family income and chronic mental and physical conditions were associated with high psychological distress in Saudi Arabia during COVID-19.

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Section: Discussionmentioning

confidence: 99%

COVID-19 related psychological distress and fears among mothers and pregnant women in Saudi Arabia

et al. 2021

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“…20 Interventions that have been assessed in COVID-19 patients include: virtual and physical psychotherapeutic approaches, e.g., cognitive behavioral therapy (CBT), emotional freedom techniques (EFT), and ultra-brief psychological interventions (UBPI); combined psychiatric and psychological interventions; technology and media; complementary and alternative therapies; self-care; spirituality and religion; and pharmacological. 21,22 In a randomized controlled clinical trial of 51 people with COVID-19 consisting of an experimental group receiving progressive muscle relaxation (PMR) technology for 30 minutes each day for five consecutive days and a control group receiving only usual care and treatment, subjects in the experimental group reported lower depressive symptoms, lower anxiety levels, and better sleep quality compared with those in the control group. 23 Another randomized control trial of 30 hospitalized patients with COVID-19 assigned to an experimental or control group reported an improvement in all outcome measures among intervention group subjects compared to controls.…”

Section: Background Rationalementioning

confidence: 99%

“…24 In that study, a short four-session crisis intervention package tailored to cover COVID-19-specific guidance was delivered by clinical psychologists. 24 Topics covered included tension reduction, relaxation, adjustment, responsibility skills enhancement, and promoting resilience. 24 Outcomes measures in the study were derived from the Depression, Anxiety, and Stress Scale (DASS21), Symptom Checklist 25 (SCL-25), and the abbreviated version of the World Health Organization Quality of Life assessment (WHOQOL-BREF).…”

Section: Background Rationalementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Post-acute sequelae of COVID-19 and adverse psychiatric outcomes: an etiology and risk systematic review protocol

Effiong

2022

Preprint

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Introduction The post-acute sequelae of COVID-19 (PASC) is a syndrome characterized by persistent COVID-19 symptoms or the onset of new symptoms following recovery from the initial or acute phase of the illness. Such symptoms often occur four or more weeks after being diagnosed with COVID-19. Although a lot of work has gone into understanding the long-term mental health effects of PASC, many questions related to the etiology and risk of this condition remain. Thus, this protocol is for a systematic review assessing the association between PASC and adverse psychiatric outcomes and whether people with PASC are at greater risk of developing an adverse psychiatric outcome than those without PASC. Methods and analysis Various medical databases (e.g., PubMed and EMBASE) will be searched for eligible articles using predefined search criteria. Gray literature will also be explored. Epidemiological observational studies and secondary analyses of randomized controlled trials that report a quantitative relationship between PASC and at least one adverse psychiatric outcome will be included. The Population, Exposure of interest, Comparator, and Outcome (PECO) framework will be used as a standardized framework for the inclusion criteria. The Joanna Briggs Institute (JBI) critical appraisal tools will be used to assess methodological quality and critically appraise the risk of bias in included studies. A random-effects meta-analysis will be conducted if possible. A narrative synthesis will be performed if a meta-analysis is impossible due to substantial heterogeneity across studies. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach will be used to rate the cumulative certainty of the evidence for all outcomes. Ethics and Dissemination Ethical approval is not required for this study. The study results will be published in a peer-reviewed journal. Prospero registration number CRD99999999999

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“…We identified 5 systematic reviews 11 - 15 that have attempted to synthesize evidence on mental health interventions for non-hospitalised children, adolescents, or adults in COVID-19, but none included any randomised controlled trials (RCTs) from COVID-19 for people not quarantined or undergoing treatment due to COVID-19. End dates of searches were between April and September 2020, and none are ongoing.…”

Section: Introductionmentioning

confidence: 99%

Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled Trials

Bonardi

Wang

et al. 2022

Can J Psychiatry

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Objectives Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection. Methods We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns. Results We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 ( N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States ( N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries ( N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified. Conclusions Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed.

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Mental health interventions following COVID-19 and other coronavirus infections: a systematic review of current recommendations and meta-analysis of randomized controlled trials

Cited by 22 publications

References 173 publications

COVID-19 related psychological distress and fears among mothers and pregnant women in Saudi Arabia

COVID-19 related psychological distress and fears among mothers and pregnant women in Saudi Arabia

Post-acute sequelae of COVID-19 and adverse psychiatric outcomes: an etiology and risk systematic review protocol

Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled Trials

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