Cognitive impairment: an (in)dependent risk factor for mortality in older men?

Loureiro, Júlia Cunha; Pais, Marcos Vasconcelos; Forlenza, Orestes Vicente

doi:10.1590/1516-4446-2020-0017

Cited by 1 publication

(1 citation statement)

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“…There is a growing body of research that links cognitive performance to mortality among older adults (Batterham et al, 2012; Batty et al, 2016; Bosworth et al, 1999; Connors et al, 2015; Lv et al, 2019; Van Gelder et al, 2007). In general, those who perform worse on cognitive tasks have higher mortality risk in later life (Loureiro et al, 2020; Perna et al, 2015; Vassilaki et al, 2015). Because previous work examining cognition has largely focused on studies with a high proportion of older women or has examined sex-related differences in cognition, there has been modest attention examining cognitive performance only among older men.…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Cognition and Mortality Among Older Black and White Men in Advanced Cognitive Training for Independent and Vital Elderly

et al. 2022

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Objective: To determine the association between baseline cognition and all-cause mortality among Black men and White men. Methods: Data were from 614 Black and White men aged ≥65 years at baseline in the Advanced Cognitive Training for Independent and Vital Elderly trial and their linked mortality information. Cox proportional hazards models were used to determine the association between baseline cognition (memory, reasoning, speed of processing, Mini Mental State Exam) and mortality risk over 20 years, adjusting for covariates. Results: Among White men, higher performance on the memory composite measure was associated with a decreased risk of all-cause mortality (HR: 0.93; 95% CI: 0.89–0.98), whereas the other cognitive measures were not associated with all-cause mortality risk. Among Black men, none of the cognitive measures was associated with all-cause mortality risk. Discussion: There is a need for future work to recruit and retain a larger sample of older Black men to better understand the cognition-mortality relationship.

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