Long-term response to cathodal transcranial direct current stimulation of temporoparietal junction in a patient with refractory auditory hallucinations of schizophrenia

Janovik, Nathalia; Cordova, Victor Hugo Schaly; Chwal, Bruna Cristine; Ogliari, Cintya Kelly Moura; Belmonte-de-Abreu, Paulo

doi:10.1590/1516-4446-2018-0330

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…Cathodal tDCS has been used for its inhibitory effect in clinical application. For example, it has been used to control hallucinations in patients with schizophrenia, a neuro-psychiatric disorder [ 6 , 7 ]. In patients with attention-deficit hyperactivity disorder (ADHD), the cathode is applied over the left dorsolateral prefrontal cortex (DLPFC) to reduce high interhemispheric inhibition (IHI) towards the right hemisphere; thus resulting in enhance inhibitory control and attention [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Non-linear dose response effect of cathodal transcranial direct current stimulation on muscle strength in young healthy adults: a randomized controlled study

Vimolratana

Lackmy-Vallée

Aneksan

et al. 2023

BMC Sports Sci Med Rehabil

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Background Transcranial direct current stimulation (tDCS) is a technique that modulates brain excitability in humans. Increasing the stimulation intensity or duration within certain limits could enhance tDCS efficacy with a polarity-dependent effect; anodal stimulation increases cortical excitability, whereas cathodal stimulation decreases excitability. However, recent studies have reported a non-linear effect of cathodal tDCS on neuronal excitability in humans, and there is no conclusive result regarding the effect of cathodal tDCS on muscle performance. Methods Our study aimed to investigate the immediate effects of different intensities (i.e., 1, 1.5, and 2 mA and sham tDCS) of cathodal tDCS on muscle strength in healthy participants. All participants [mean age 23.17 (3.90) years] were recruited and randomly allocated into four groups (1, 1.5, and 2 mA cathodal tDCS and sham tDCS). Muscle strength in bilateral upper and lower extremities was measured before and immediately after tDCS using a handheld dynamometer. Results Our results showed that cathodal tDCS at 1 and 1.5 mA reduced muscle strength bilaterally in upper and lower extremity muscles, whereas stimulation at 2 mA tended to increase muscle strength on the dominant limb. Conclusion These findings support the non-linear effects of cathodal tDCS on muscle strength, which should be considered for the clinical use of tDCS in motor rehabilitation. Trial registration: NCT04672122, date of first registration 17/12/2020.

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