Alcohol-related blackouts among college students: impact of low level of response to alcohol, ethnicity, sex, and environmental characteristics

Gonçalves, Priscila Dib; Smith, Tom L.; Anthenelli, Robert M.; Danko, George P.; Schuckit, Marc A.

doi:10.1590/1516-4446-2016-2165

Cited by 11 publications

(6 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With regard to demographic factors, findings that ARB + participants were significantly older and more likely to be White have been reported in other literature, particularly among college students (67,70,71). The association between older age and ARBs at each timepoint may reflect NCANDA inclusion criteria which allowed a subset of older participants to exceed alcohol use thresholds (31).…”

Section: Alcohol-related Blackouts In the National Consortium On Alco...supporting

confidence: 55%

A Longitudinal Examination of Alcohol-Related Blackouts as a Predictor of Changes in Learning, Memory, and Executive Function in Adolescents

et al. 2022

View full text Add to dashboard Cite

IntroductionIn adolescents, the relationship between alcohol-related blackouts (ARBs) and distinct cognitive changes lasting beyond intoxication is unclear. We examined ARBs as a predictor of persistent changes in the development of learning, memory, and executive function in participants from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study.MethodsDescriptive analyses of the NCANDA sample (N = 831, 50.9% female, 12–21 years at baseline) identified ARB patterns within participants with an ARB history (n = 106). Latent growth curve modeling evaluated ARB-related performance changes on four neuropsychological measures across five years, excluding baseline data to reduce the magnitude of practice effects over time (n = 790). Measures included the Penn Conditional Exclusion Test (PCET), Penn Letter N-back Test (PLBT), Penn Facial Memory Test immediate (PFMTi), and delayed (PFMTd) recognition trials, and the Rey Complex Figure Test copy (RCFTc), immediate recall (RCFTi), and delayed recall (RCFTd) trials. Multivariate models were fit for raw accuracy scores from each measure, with ARB history (i.e., presence of past-year ARBs) as the main independent variable. Age, sex, race, socioeconomic status, assessment site, and alcohol use (i.e., past-year frequency) were included as covariates. Interaction effects between ARB history and alcohol use frequency were tested.ResultsBy year five, 16% of participants had experienced at least one ARB (59% of whom reported > 1 ARB and 57% of whom had an ARB lasting > 1 h). After controlling for demographics and alcohol use, ARB history predicted attenuated PFMTd performance growth at year one. Interaction effects between ARB history and alcohol use frequency predicted attenuated PFMTd performance growth at years one and two. ARB history predicted attenuated RCFTi and RCFTd performance growth by year four, but not PCET or PLBT performance over time. By contrast, greater past-year alcohol use predicted attenuated PFMTi and PFMTd performance growth between years two and four in adolescents without an ARB history.ConclusionWe found that ARBs predict distinct, lasting changes in learning and memory for visual information, with results suggesting that the developing brain is vulnerable to ARBs during adolescence and emerging adulthood.

show abstract

Section: Alcohol-related Blackouts In the National Consortium On Alco...supporting

confidence: 55%

A Longitudinal Examination of Alcohol-Related Blackouts as a Predictor of Changes in Learning, Memory, and Executive Function in Adolescents

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Because a low LR is hypothesized to impact on how much a person drinks per occasion and does not relate closely to impulsivity, LR does not correlate highly with drinking frequency (Schuckit, ). Examples of significant positive correlations between SRE scores and future heavier alcohol intake and alcohol problems include data from the San Diego Prospective Study (SDPS), the Collaborative Study of the Genetics of Alcoholism (COGA), the U.K.‐based Avon Longitudinal Study of Parents and Children (ALSPAC), and others (e.g., Chung and Martin, ; Goncalves et al., ,b; Schuckit and Smith, ; Schuckit et al., , ). SRE‐based LR values are higher in men than women (i.e., men have a low LR per drink) (Eng et al., ; Schuckit et al., , , , ) and European Americans (EAs) compared to African Americans (AAs) and Asian individuals (Luczak et al., , ; Park et al., ; Pedersen and McCarthy, ).…”

mentioning

confidence: 99%

Performance of the Self‐Report of the Effects of Alcohol Questionnaire Across Sexes and Generations

Schuckit

Smith

Rana

et al. 2019

Alcoholism Clin & Exp Res

Self Cite

View full text Add to dashboard Cite

Background: Low level of responses (low LRs) to alcohol established using the Self-Report of the Effects of Alcohol (SRE) questionnaire are genetically influenced phenotypes related to heavy drinking and alcohol problems. To date, most studies using SREs focused on scores for the number of drinks needed for effects across the first 5 times of drinking (SRE-5), and few evaluated scores that also included the prior 3 months and heaviest drinking periods (SRE-T). This paper evaluates characteristics of SRE-5 and SRE-T within and across generations.Methods: Data were extracted from 407 participants across 2 generations of 107 families in the San Diego Prospective Study (SDPS). Pearson's product-moment correlations for SRE-5 and SRE-T were determined across first-degree relatives both within and across generations and sexes, as well as correlations of each measure to maximum drinking quantities and alcohol problems.Results: Responding to 4 hypotheses, first the analyses demonstrated significant within-generation positive correlations for both SRE measures across brother-brother and sister-sister pairs as well as cross-generation correlations for fathers and sons, although correlations for mothers and daughters were not robust. Second, both SRE-5 and SRE-T correlated with maximum drinks and alcohol problems for both sexes and both generations. Third, within parental and offspring generations SRE-T correlated more robustly than SRE-5 to maximum drinks and alcohol problems. Fourth, across generations SRE values for sons were more closely related to drinking quantities and problems than for their fathers, but the mother-daughter SRE relationships to adverse alcohol characteristics were not different.Conclusions: Both the SRE-5 and SRE-T offered useful information about propensities toward heavier drinking and alcohol problems in SDPS families. Correlations with adverse alcohol outcomes were greater for the more broad-based SRE-T, but both scores appeared to be genetically influenced and continue to operate in a robust manner in both generations of these families.

show abstract

“…A low LR involves the need for higher numbers of drinks and higher BACs to produce alcohol-related changes in feelings of intoxication, standing steadiness, and/or alterations in physiologic effects of alcohol, including those seen in electroencephalographic, event-related potentials/oscillations, brain connectivity, hormonal, and/or functional magnetic imaging measures (McKenna et al, 2022;Schuckit, 2022). These effects have been observed even after controlling for recent drinking patterns and demographic characteristics, (e.g., Gonçalves, Smith, et al, 2017;Schuckit, 2018).…”

Section: Introductionmentioning

confidence: 99%

Do personality characteristics predict future alcohol problems after considering current demography, substance use, and alcohol response?

Schuckit

Smith

Danko

et al. 2023

Alcohol: Clinical and Experimental Research

Self Cite

View full text Add to dashboard Cite

Background Several personality traits predict future alcohol problems but also relate to demographic and substance‐related variables that themselves correlate with later adverse alcohol outcomes. Few prospective studies have evaluated whether personality measures predict alcohol problems after considering current demographic and substance‐related variables. Methods Data from 414 drinkers without alcohol use disorder (AUD) from the Collaborative Study on the Genetics of Alcoholism (average age 20, 44% male) were followed over an average of 9 years. Time 1 (baseline) demography, AUD family history (FH), substance use and problems, and psychiatric histories were gathered using a standardized interview; the Level of Response (LR) to alcohol was measured by the Self‐Report of the Effects of alcohol (SRE) questionnaire; and seven personality dimensions were extracted from the NEO Five‐Factor Personality, Barratt, and Zuckerman scales. Analyses involved product–moment correlations of each baseline measure with the highest number of DSM‐IV AUD criteria endorsed in any follow‐up period, and hierarchical regression analyses evaluated whether the personality domains added significantly to the prediction of the outcome after adjusting for other baseline variables. Results Significant correlations with the outcome were observed for baseline age, sex, length of follow‐up, AUD family history, past cannabis use, and all alcohol‐related baseline variables, including SRE‐based LR, but not prior mood or anxiety disorders. All personality characteristics except extraversion also correlated with outcomes. A hierarchical regression analysis that included all relevant personality scores together demonstrated significant contributions to the prediction of future alcohol problems for demographics in Step 1; demographics and most baseline alcohol items, including response level, in Step 2; and cannabis use in Step 3; after which demographics, LR, baseline alcohol problems, cannabis use, and higher sensation seeking added significantly in Step 4. Regression for each personality domain separately revealed significant contributions to Step 4 for all personality domains except openness. Lower levels of response to alcohol added significantly to all regression analyses. Conclusions Most tested personality scores and lower levels of response to alcohol contributed to predictions of later alcohol problems even after considering baseline demographic and substance use measures.

show abstract

Alcohol-related blackouts among college students: impact of low level of response to alcohol, ethnicity, sex, and environmental characteristics

Cited by 11 publications

References 35 publications

A Longitudinal Examination of Alcohol-Related Blackouts as a Predictor of Changes in Learning, Memory, and Executive Function in Adolescents

A Longitudinal Examination of Alcohol-Related Blackouts as a Predictor of Changes in Learning, Memory, and Executive Function in Adolescents

Performance of the Self‐Report of the Effects of Alcohol Questionnaire Across Sexes and Generations

Do personality characteristics predict future alcohol problems after considering current demography, substance use, and alcohol response?

Contact Info

Product

Resources

About