Assessment of the strength of recommendation and quality of evidence: GRADE checklist. A descriptive study

Bezerra, Camila Torres; Grande, Antônio José; Galvão, Vivianny Kelly; Santos, Douglas Henrique Marin dos; Atallah, Álvaro Nagib; Silva, Valter

doi:10.1590/1516-3180.2022.0043.r1.07042022

Cited by 4 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For instance, some studies did not implement allocation concealment, blinding, and intention to treat analysis. According to Bezerra et al 55 methodological flaws and heterogeneity affect the quality of evidence. Therefore, fixing current methodological pitfalls by adhering to allocation concealment, intention to treat analysis, blinding of outcome assessors needs to be the focus of future research in PEIs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effectiveness of psychoeducation interventions in reducing negative psychological outcomes and improving coping skills in caregivers of children with cancer: A systematic review and meta‐analysis

Phiri,

Li,

Cheung

et al. 2023

Psycho-Oncology

View full text Add to dashboard Cite

PurposePsychoeducation interventions (PEIs) have been used as an adjunct treatment for negative psychological outcomes in caregivers of children with cancer. This systematic review and meta‐analysis aimed to evaluate the evidence on the effectiveness of PEIs in reducing anxiety and depressive symptoms and improving health‐related quality of life (HRQoL) and coping skills in caregivers of children with cancer.MethodTen English databases were searched to identify studies on PEIs for caregivers of children with cancer. Studies inclusion criteria were as follows: (1) participants who were caregivers of children with cancer receiving treatment; (2) psychoeducational interventions assessing anxiety, depressive symptoms, HRQoL, and coping outcomes; and (3) usual care, waitlist, or active control as a control group. Meta‐analysis and narrative synthesis were used to analyse data.ResultsFourteen randomised control trials were included. PEIs have a beneficial effect on anxiety levels (SMD: −0.59, 95% CI [−0.92, −0.25], p = 0.0007), quality of life (SMD: −0.31, 95% CI [−0.00, −0.61], p = 0.05) and depressive symptoms (SMD: −1.18, 95% CI [−2.08, −0.28], p = 0.01) immediately post‐intervention. The effect of PEIs was maintained at long‐term follow‐up on depressive symptoms (SMD: −0.52, 95% CI [−1.54, −0.36], p = 0.0004). Similarly, the synthesised data suggest that PEIs are effective in improving coping skills.ConclusionThe review provides evidence that PEIs effectively reduce negative psychological outcomes and improve coping skills in caregivers of children with cancer. However, due to methodological flaws and heterogeneity of the interventions evaluated, more research is needed to determine the most effective PEI design and improve the quality of evidence.

show abstract

Section: Discussionmentioning

confidence: 99%

“…For instance, some studies did not implement allocation concealment, blinding, and intention to treat analysis. According to Bezerra et al 55 . methodological flaws and heterogeneity affect the quality of evidence.…”

Section: Discussionmentioning

confidence: 99%