Myalgia-arthralgia syndrome induced by docetaxel in oncology: the wolf disguised as a sheep

Abstract

Taxanes are anti-microtubulin drugs that have a broad spectrum of antitumor activity. They are probably the most widely used cytotoxics. 1 Their common adverse effects include bone marrow suppression, hypersensitivity or skin reactions, alopecia and peripheral sensory neuropathy 1. However, the myalgia-arthralgia syndrome (MAS), which is frequent in daily practice, remains