2016
DOI: 10.1590/1516-3180.2016.0099220516
|View full text |Cite
|
Sign up to set email alerts
|

Validity of Klotho, CYR61 and YKL-40 as ideal predictive biomarkers for acute kidney injury: review study

Abstract: CONTEXT AND OBJECTIVE: Acute kidney injury (AKI) is still a headache for clinicians and scientists as a possible reason for increased death among intensive care unit (ICU) patients after invasive cardiac surgery. Furthermore, the diagnostic process for AKI using conventional biomarkers is not sufficient to ensure early warning of this condition because of the morbid influence of non-renal factors that definitively delay the time for the prognosis. These imposed limitations have led to significant amounts of re… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2021
2021
2022
2022

Publication Types

Select...
4
1

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(1 citation statement)
references
References 63 publications
0
1
0
Order By: Relevance
“…Researches have shown that Klotho is not only an anti-aging gene but also a tumor suppressor gene that has the function of protecting kidney and inhibiting RCC. The downregulation of Klotho may be closely related to the poor prognosis of RCC ( 19 , 20 ). DNA methylation is an important nucleic acid modification, which needs the catalysis of DNA methyltransferase ( 21 , 22 ).…”
Section: Introductionmentioning
confidence: 99%
“…Researches have shown that Klotho is not only an anti-aging gene but also a tumor suppressor gene that has the function of protecting kidney and inhibiting RCC. The downregulation of Klotho may be closely related to the poor prognosis of RCC ( 19 , 20 ). DNA methylation is an important nucleic acid modification, which needs the catalysis of DNA methyltransferase ( 21 , 22 ).…”
Section: Introductionmentioning
confidence: 99%