Mortality due to cardiovascular diseases in the Americas by region, 2000-2009

Gawryszewski, Vilma Pinheiro; Marinho, Fátima

doi:10.1590/1516-3180.2014.1322604

Cited by 15 publications

(12 citation statements)

References 8 publications

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“…Cardiovascular diseases are the leading cause of mortality in the worldwide 22 and a variety of pharmaceutical drugs have been used to target specifically pathological processes for myocardial injury. Yet, these compounds are often associated with side effects and currently there is still no effective therapy to prevent heart injuries 23 .…”

Section: Discussionmentioning

confidence: 99%

Cardioprotective activity of iron oxide nanoparticles

Xiong

Wang

Feng

et al. 2015

Sci Rep

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Iron oxide nanoparticles (IONPs) are chemically inert materials and have been mainly used for imaging applications and drug deliveries. However, the possibility whether they can be used as therapeutic drugs themselves has not yet been explored. We reported here that Fe2O3 nanoparticles (NPs) can protect hearts from ischemic damage at the animal, tissue and cell level. The cardioprotective activity of Fe2O3 NPs requires the integrity of nanoparticles and is not dependent upon their surface charges and molecules that were integrated into nanoparticles. Also, Fe2O3 NPs showed no significant toxicity towards normal cardiomyocytes, indicative of their potential to treat cardiovascular diseases.

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Section: Discussionmentioning

confidence: 99%

Cardioprotective activity of iron oxide nanoparticles

Xiong

Wang

Feng

et al. 2015

Sci Rep

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“…The causes of death due to hypertensive diseases have tended to increase in the last decades in Brazil (4) and in the United States, where they increased by 23.1% in the period from 2000 to 2013 (5) . The mortality trends of cardiovascular diseases in the regions of the Americas, since the 2000s, have declined by 29.5% in North America, lower falls (14.1%) in Latin America and a decrease of only 10.9% in the Caribbean region (30) .…”

Section: Discussionmentioning

confidence: 99%

Hypertension is the underlying cause of death assessed at the autopsy of individuals

Coelho

Ferretti-Rebustini

Suemoto

et al. 2019

Rev. esc. enferm. USP

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Objective: To analyze hypertension and its relationship with the causes of death identified by the autopsy. Method: Cross-sectional study analyzed 356 participants belonging to the Brazilian Aging Brain Study Group, over 50 years of age, autopsied at the Sao Paulo Autopsy Service between 2004 to 2014. A clinical interview was conducted with the informant of the deceased. Hypertension was defined by reporting the disease and/or use of antihypertensive medication, by the informant of the deceased. Descriptive analyzes and bivariate and multivariable associations were performed. Results: The prevalence of hypertension was 66.2% and it was the second leading cause of death (25.6%) identified by autopsy, preceded by atherosclerosis (37.8%). The variables associated with hypertension were: female gender (OR=2.30 (1.34-3.90)); living with partner [OR=0.55 (0.32-0.92)]; Body Mass Index [OR=1.14 (1.08-1.22)] and history of diabetes [OR=2.39 (1.34-4.27)]. Conclusion: The prevalence of hypertension was high, and it was the second most common underlying cause of death. The gold standard for the definition of cause of death, the autopsy, shows important results, which confirmed the relevance of hypertension as a public health problem.

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“…11 In Western Europe, total CVD mortality has markedly declined with decreases observed also for IHD and stroke 1213 North American countries have had higher declines of CVD death rates when compared with countries in Latin America and the non-Latin Caribbean 14…”

Section: Discussionmentioning

confidence: 99%

Analysis of mortality trends due to cardiovascular diseases in Panama, 2001–2014

et al. 2016

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ObjectiveCardiovascular diseases (CVDs) are still the leading cause of death worldwide despite the recent decline in mortality rates attributable to CVD in Western Europe and the Americas. The aim of this study is to investigate mortality trends due to ischaemic heart disease (IHD) and stroke in Panama from 2001 to 2014, as well as the mortality differences by sex and age groups.MethodsData were obtained from the National Mortality Register. The International Classification of Diseases 10th revision codes (ICD-10) I20–I25 and I60–I69 were used for IHD and stroke, respectively. Age-adjusted mortality rates were calculated using the world population of the WHO as standard. Trends were analysed using Joinpoint Regression Program and annual percentage changes (APC) were estimated.ResultsFrom 2010, the IHD mortality trend began to decline in the whole population of Panama (APC −4.7%, p<0.05). From 2001 to 2014, a decline in the trend for IHD mortality was observed (APC −1.7%, p<0.05) in women, but not in men. Stroke mortality showed a significant annual decline during the study period (APC −3.8%, p<0.05) and it was more pronounced in women (APC −4.5%, p<0.05) than in men (APC −3.3%, p<0.05).ConclusionsIn Panama, the mortality rates from IHD and stroke have declined in recent years. Better access to healthcare, improved treatment of acute IHD and stroke, low tobacco consumption and better control of hypertension probably account for a significant part of this mortality reduction.

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Mortality due to cardiovascular diseases in the Americas by region, 2000-2009

Cited by 15 publications

References 8 publications

Cardioprotective activity of iron oxide nanoparticles

Cardioprotective activity of iron oxide nanoparticles

Hypertension is the underlying cause of death assessed at the autopsy of individuals

Analysis of mortality trends due to cardiovascular diseases in Panama, 2001–2014

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