Effect of fatty Amazon fish consumption on lipid metabolism

Abstract

OBJECTIVE: The present study aimed to evaluate the effect of feeding diets enriched with fatty fish from the Amazon basin on lipid metabolism. METHODS: Male Wistar rats were divided into four groups: control group treated with commercial chow; Mapará group was fed diet enriched with Hypophthalmus edentatus; Matrinxã group was fed diet enriched with Brycon spp.; and, Tambaqui group was fed diet enriched with Colossoma macropomum. Rats with approximately 240g±0.60 of body weight were fed ad libitum for 30 days, and then were sacrificed for collection of whole blood and tissues. RESULTS: The groups treated with enriched diets showed a significant reduction in body mass and lipogenesis in the epididymal and retroperitoneal adipose tissues and carcass when compared with the control group. However, lipogenesis in the liver showed an increase in Matrinxã group compared with the others groups. The levels of serum triglycerides in the treated groups with Amazonian fish were significantly lower than those of the control group. Moreover, total cholesterol concentration only decreased in the group Matrinxã. High Density Lipoprotein cholesterol levels increased significantly in the Mapará and Tambaqui compared with control group and Matrinxã group. The insulin and leptin levels increased significantly in all treatment groups. CONCLUSION: This study demonstrated that diets enriched with fatty fish from the Amazon basin changed the lipid metabolism by reducing serum triglycerides and increasing high density lipoprotein-cholesterol in rats fed with diets enriched with Mapará, Matrinxã, and Tambaqui.

Changes in Metabolic Regulation and the Microbiota Composition after Supplementation with Different Fatty Acids in db/db Mice

“…TC and PAI increased significantly in the lyophilized group, but not with the consumption of enriched diet and coconut oil (Table 4). These results are similar to those of Amaral et al [64], who showed that the Wistar rats did not modify their total cholesterol levels in the groups treated with diets enriched with fatty fish from the Amazon. In contrast, in a study with Swiss albino mice supplemented with fatty acids derived from the Caryocar brasiliense walnut, TC and HDL-c increased with no changes in the atherogenic index and triacylglycerides [65].…”

NMR in Analysis of the Nutritional Value of Lipids from Muscles and Livers of Wild Amazonian Fishes with Different Eating Habits over Seasonal Variation

“…[48] This is based on omega 6 and 3 ratio but also based on the fact that fatty Amazon fish can change the lipid metabolism effectively lowering plasma Low Density Lipoprotein (LDL) and increasing High Density Lipoprotein (HDL). [49] While when we interpreted in light of the crosstalk between the ecological environment and fish physiology, its fact that species sharing the same food habits can have similar substrates for the endogenous synthesis of lipids, these seem to be used to attend the specific fish metabolism. [50] Amazon fishes developed different adaptations to survive in the challenging environment of the region, such as migratory habits and mechanisms to deal with hypoxia exposure.…”

Hematology and plasma biochemistry in rats fed with diets enriched with fatty fishes from Amazon region

“…The diets were prepared as recommended by Souza et al 19 . In summary, the fish muscle was deboned mechanically (Baader 694 Bone Separator) and immediately frozen to -30 o C. The bulk of the experimental diets wasthe commercial chow Nuvilab CR-1 (Nuvilab ® Nutrientes Ltda, Curitiba, PR).…”