Association of genitourinary infections and cervical length with preterm childbirth

Bernardo, F.M.M.; Veiga, E C A; Quintana, Silvana Maria; Camayo, F.J.A.; Batista, Rosângela Fernandes Lucena; Alves, Maria Teresa Seabra Soares de Britto; Bettiol, Heloísa; Barbieri, Marco Antônio; Cardoso, Viviane Cunha; Cavalli, Ricardo de Carvalho

doi:10.1590/1414-431x202010235

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…In our study, the PTB prevalence of mothers with vaginal infections coincided with the published data, while 8.2% PTB prevalence observed in UTI patients was lower than the reported 15 to 32.9% 45,47 . African-American ancestry, often related to low socioeconomic level and less prenatal care, was a risk factor for women with UTI in our sample.…”

Section: Vaginal and Urinary Tract Infectionssupporting

confidence: 91%

Diseases during pregnancy in a large unselected South American sample

Santos

Campaña

Heisecke

et al. 2022

Rev. bras. epidemiol.

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Objective: Our aim was to describe the prevalence of diseases during pregnancy and the association between fetal exposure to the most frequent maternal diseases and the risk of preterm (PTB) and/or small for gestational age (SGA) newborns in an unselected sample of women who gave birth in South American countries. Methods: We conducted a descriptive, cross-sectional study including 56,232 mothers of non-malformed infants born between 2002 and 2016, using data from the Latin American Collaborative Study of Congenital Malformations (ECLAMC). Diseases with higher- than-expected PTB/SGA frequencies were identified. Odds ratios of confounding variables for diseases and birth outcomes were calculated with a multivariable logistic regression. Results: Of the 14 most reported diseases, hypertension, genitourinary infection, epilepsy, hypothyroidism, diabetes, and HIV/AIDS showed higher PTB and/or SGA frequencies. Advanced and low maternal age, previous fetal loss, low socioeconomic level, and African-American ancestry were associated with PTB, while advanced maternal age, primigravidity, previous fetal loss, low socioeconomic level, and African-American ancestry were associated with SGA. After adjusting for the associated variables, the identified illnesses maintained their association with PTB and all, except epilepsy, with SGA. Conclusion: The description of an unselected population of mothers allowed identifying the most frequent diseases occurring during gestation and their impact on pregnancy outcomes. Six diseases were associated with PTB and two with SGA newborns. To the best of our knowledge, there are no similar reports about women not intentionally selected by specific diseases during pregnancy in South American populations.

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Section: Vaginal and Urinary Tract Infectionssupporting

confidence: 91%

Diseases during pregnancy in a large unselected South American sample

Santos

Campaña

Heisecke

et al. 2022

Rev. bras. epidemiol.

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“…Nine articles had a longitudinal focus. Five of them addressed predictors measured during pregnancy and assessed outcomes at the time of delivery: pre-gestational BMI and its association with newborn weight (7); uterine artery pulsatility index and other maternal attributes such as risk factors for the development of gestational hypertension (8); measurement of cervical length, genitourinary infection, bacterial vaginosis, and prematurity (9); effect of genetic variants on the occurrence of intrauterine growth restriction (10); and consumption of soft drinks at 20-25 weeks of gestation, metabolic profile, and arterial hypertension (11). The other studies evaluated the long-term effects on the generations born during the cohorts: determinants of early weaning at less than 3 months and between 4 and 5 months of age (12); the importance of maternal cigarette and alcohol consumption during pregnancy and cognitive developmental delays in children after the second year of life (13); determinants of delayed first dental visit (not visiting a dentist before the age of 7) (14); and cesarean birth and mood disorders in adolescence (15).…”

Section: Presentation Of Issue 54(1)2021mentioning

confidence: 99%

Being born and growing up in the Ribeirão Preto and São Luís cohorts

Leal

2021

Braz J Med Biol Res

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This thematic issue consists of 14 articles derived from studies of the BRISA birth cohort (Ribeirão Preto, State of São Paulo and São Luís, State of Maranhão, northeastern Brazil, a socially and economically less developed region). In these more than 40 years of existence, these cohorts have been able to document the increase in women's education, the improvement of health conditions, the creation of a public Unified Health System (SUS) that provides universal and free access to health care, eradication of hunger, and transition of the nutritional status characterized by a decrease in malnutrition rates and an increase in obesity in Brazil. Particularly in reproductive health, the country experienced a significant drop in fertility, a decrease in maternal and child mortality, and an increase in breastfeeding rates. Universal access to prenatal care and hospital delivery was accompanied by an excessive number of cesareans without clinical indication and early-term births and premature births, largely due to scheduled cesareans. Articles with a longitudinal and transversal methodological approach are presented, using structural equation analysis and propensity score, together with multivariate regressions, which gave a robust analytical treatment to articles in this thematic issue.

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Effect of bacterial vaginosis on preterm birth: a meta-analysis

Mohanty

Doke

Khuroo

2022

Arch Gynecol Obstet

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Purpose Bacterial vaginosis is a common genital tract disorder. It can lead to preterm birth but its contribution and extent is equivocal. Bacterial vaginosis is a treatable cause of preterm birth if diagnosed and treated correctly. The study desired to con rm the relationship between bacterial vaginosis and preterm.Methods It was a meta-analysis. Articles published from 2008 to 2018 were included. The studies conducted to measure the strength of association between Bacterial Vaginosis and Preterm Birth by any statistical test were included. Studies with only conceptual aspects and qualitative data were excluded from the meta-analysis. Four search engines were identi ed, PubMed, Google Scholar, Cochrane, and LILAC. Forest plots were plotted separately for Odds Ratio (OR) and Relative Risk.Results After extensive search 11 studies giving 14 relevant results with 20,894 participants were included. This meta-analysis proves that Bacterial Vaginosis is strongly associated with preterm birth.The risk of preterm delivery is >2-folds in women with bacterial vaginosis (OR, 2.79; 95% CI, 2.29 to 3.41).The combined or pooled risk ratio (RR) of pregnant women with bacterial vaginosis having a preterm birth or preterm delivery is 1.52 (RR, 95% C.I.=1.33 to 1.74). ConclusionOur study shows a strong association between Bacterial vaginosis and preterm birth. The study concludes that investigation for bacterial vaginosis and management accordingly should be a part of the routine examination of a pregnant woman. The health system must initiate this strategy at the earliest to reduce prevalence of preterm births and thereby neonatal mortality.

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Association of genitourinary infections and cervical length with preterm childbirth

Cited by 3 publications

References 27 publications

Diseases during pregnancy in a large unselected South American sample

Diseases during pregnancy in a large unselected South American sample

Being born and growing up in the Ribeirão Preto and São Luís cohorts

Effect of bacterial vaginosis on preterm birth: a meta-analysis

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