Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review

Lima, E.B.C.; Sousa, Caren Nádia Soares de; Meneses, L.N.; Ximenes, Naiara Coelho; Júnior, Manuel Alves Santos; Vasconcelos, Germana Silva; Lima, N.B.C.; Patrocínio, Manoel Cláudio Azevedo; Macedo, Danielle; Vasconcelos, Silvânia Maria Mendes

doi:10.1590/1414-431x20154773

Cited by 181 publications

(117 citation statements)

References 56 publications

(64 reference statements)

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“…The reason that can justify such contradiction is might be due to the fatty acids contents in the VCO. It is reported that content of active compound present in the plant might vary according to the geographical area that includes soil content and seasonal variations [9]. Since the coconut used in this project are collected from a local farm in Malaysia, and the VCO used in the contradict claims were from India, the geographical difference might have influence in the active compound of VCO which in this case, the fatty acids to be different.…”

Section: Advances In Health Science Research Volumementioning

confidence: 98%

“…Prominent and recent studies have shown that unrefined coconut oil, Virgin Coconut oil (VCO) can be exceptionally advantageous, as it possessed antimicrobial characteristic towards a broad range of species, ranging from Mycobacterium species, Gram-positive and Gramnegative bacteria [8,9]. Differ from other common oils which are usually composed of long chain fatty acids, coconut oil and VCO are concentrated with short and medium chain fatty acids, and therefore classified as medium chain fatty acids (MCFA) [9]. Eastern scholars had outlined that, of the fatty acids present in coconut oil, lauric acid (C:12:0) is proven to be more active as antibacterial agent compared to caprylic acid (C8:0), capric acid (C10:0), and myristic acid (C14:0) [11].…”

Section: Introductionmentioning

confidence: 99%

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The Comparative Antimicrobial Effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against Dental Caries-Related Pathogens

Haron¹,

Abllah²,

Nasir³

2018

Proceedings of the International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)

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Abstract-The present-day diet is astoundingly cariogenic, owing to the fact that high food intake with plenty of fermentable carbohydrates present in them. Classic regime against dental caries such as fluoride is often not able to cope with the resultant massive cariogenic challenge. Therefore, demands of alternatives for the classic regime in arresting issues related to oral health are always on the increase. In contemplation to improve and further develop novel antimicrobial compound, a great deal of research has gone into optimizing a lot of components presently available in natural sources which may help to contribute to the antimicrobial activity. The virgin coconut oil (VCO) is a case in point and has been the focus for decades as it has proven to possess antimicrobial features on Gram positive bacteria. Recently, there is a patterned Activated Virgin Coconut Oil (AVCO) that reported to have a broad antimicrobial spectrum. However, information regarding the inhibitory of AVCO and VCO against dental cariesrelated pathogens is yet to be established. In this study, we compared the antimicrobial effect of AVCO obtained from KL trading, Selangor, Malaysia, and VCO extracted in our laboratory. Their MIC and MBC against the selected dental caries-related pathogen; Streptococcus mutans, Lactobacillus casei and Candida albicans were determined. Out of the three tested organisms, L. casei was subjected to have a higher sensitivity towards AVCO (MIC: 0.78 mg/ml and MBC: 1.56mg/ml), followed by C. albicans (MIC: 3.12 mg/ml and MBC: 6.24 mg/ml) and S. mutans (MIC: 6.24 mg/ml and MBC: 24.96 mg/ml). In contrast to a positive finding of AVCO, VCO has shown no inhibitory effect on all tested dental caries-related pathogens. Furthermore, the time killing assay revealed that AVCO showed relatively quick-killing activity at the 8 hours of time for all tested organism. These finding correlates with that of AVCO possess bactericidal activity, thereby allowing the possible classification of the AVCO as being a bactericidal agent.

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Section: Advances In Health Science Research Volumementioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

The Comparative Antimicrobial Effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against Dental Caries-Related Pathogens

Haron¹,

Abllah²,

Nasir³

2018

Proceedings of the International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)

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“…For instance, a tea from the husk fibers is used in Brazil against diarrhea [83] and in Haiti against amenorrhea [84], a tea from the roots would treat diarrhea and stomach pains in Papua New Guinea [85], while coconut oil would prevent hair loss and promote wound healing according to Fijan and Indonesian beliefs [86]. These actions may be associated with the presence of phenols, tannins, leucoanthocyanidins, flavonoids, triterpenes, steroids, alkaloids, triterpenes, saponins, and condensed tannins in several parts of the plant [87], as well as that of vitamin E and a number of fatty acids in coconut oil [88]. For these reasons, coconut oil is an important base ingredient of shower gels, shampoos and hair conditions, moisturizers, emollients, nourishing agents, body butters, fragrances, sunscreens, formulations to prevent drying of the skin, anti-redness agents, antiageing agents, and remedies for skin infections [89].…”

Section: Cocos Nucifera Lmentioning

confidence: 99%

“A thing of beauty is a joy forever”. Plants and plant-based preparations for facial care in Suriname

Mans¹,

Grant²

2017

Clin Med Invest

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People have probably used plant-based substances to improve their appearance since the existence of mankind. The first documented use of cosmetics dates back to 3,000 BC from ancient Egypt, but it is safe to say that this custom has been (and still is) an integral part of daily life in all civilizations. The initial use of plantderived makeup -sometimes supplemented with paints and dyes -has come full circle and is back with the contemporary trend of using beauty products that are mainly derived from plant sources. The Republic of Suriname (South America) is renowned for its extensive ethnopharmacological knowledge and unique plant biodiversity that provides ample raw material that can be processed into cosmetics and cosmeceuticals. This paper gives some historical highlights on the use of makeup throughout the world with the emphasis on naturally-derived products; focuses on the herbal cosmetics industry in Suriname; extensively addresses the scientific rationale for incorporating extracts from plants in cosmetics and cosmeceuticals in the country; and concludes with the conditions to establish a beauty products industry in Suriname.

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“…In addition, other properties such as anti-hypertensive, cardio-protective, anti-seizure, cytotoxicity, hepatoprotective, vasodilation, nephronprotective, and anti-osteoporosis effects were also reported. Because each part of C. nucifera has different phytoconstituents, the pharmacological and biological effects of the plant vary according to the parts of the plant evaluated [7].…”

Section: Introductionmentioning

confidence: 99%

A Study on the Bioactive Potential of Fresh and Dried Sprouts of Cocos Nucifera L.–an in Vitro and in-Silico Approach

Valli¹,

Gowrie²

2017

Int J Pharm Pharm Sci

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Objective: The main objective of the study is to analyze the medicinal properties, by giving scientific validation to the existing bioactive compounds present in the coconut sprouts and recommending the coconut sprouts as a natural product for the treatment of bacterial infection leading to inflammations. Methods:Phytochemical screening by qualitative and quantitative analysis of the primary and secondary constituents were carried out in aqueous and methanol extracts of the coconut sprouts (fresh and dried) using standard procedures. The phytochemicals were characterized using FT-IR, TLC and GC-MS analysis. Antibacterial activity was studied against several human pathogens by agar well diffusion method. Antioxidant activity using Reducing power, Hydrogen peroxide scavenging and DPPH radical scavenging methods and Anti-inflammatory activity through protein denaturation method were carried out. Further confirmation of the functional role of the phytoconstituent through in-silico docking was studied. Results:The qualitative phytochemical screening revealed the presence of essential phytoconstituents. The quantitative analysis revealed the presence of maximum Carbohydrates (0.60±0.1 mg/g), Proteins (39±0.8 mg/ml), Flavonoids (0.28±0.1 mg QE/g) and Terpenoids (95±1.2 mg/g) in methanolic fresh coconut sprout extract with respective standards. Maximum zone of inhibitions were shown by Shigella flexneri, Salmonella typhi and Klebsiella pneumoniae. Antioxidant and anti-inflammatory studies proved the presence of therapeutic bioactive potential in the sample. Through in-silico analysis, docking studies were performed to confirm the functional role of the specific therapeutic phytochemical. Conclusion:The fresh coconut sprouts are natural, economically potent food source for human health and can be a nutrient supplement with cost effective approach. The dried sprouts can also be recommended to the food industry for the large-scale production of nutrient-based foods with a quality check.

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Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review

Cited by 181 publications

References 56 publications

The Comparative Antimicrobial Effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against Dental Caries-Related Pathogens

The Comparative Antimicrobial Effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against Dental Caries-Related Pathogens

“A thing of beauty is a joy forever”. Plants and plant-based preparations for facial care in Suriname

A Study on the Bioactive Potential of Fresh and Dried Sprouts of Cocos Nucifera L.–an in Vitro and in-Silico Approach

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