“…A wide range of histological methods, including autoradiography and in situ hybridization, indicate the presence of α2 receptors in the pontine nuclei, including the parabrachial nuclei and the KF (Andrade, Andrade‐Franzé, Paula, De, & De, 2014; Davern, 2014; Herbert & Flügge, 1995; Scheinin et al., 1994; Unnerstall, Fernandez, & Orensanz, 1985). Specifically, moderate to intense labeling for α2A and α2B‐receptor subtypes has been documented in the KF of multiple species (Rosin et al., 1993; Strazielle, Lalonde, Hébert, & Reader, 1999; Tavares, Handy, Bogdanova, Rosene, & Gavras, 1996; Wang et al., 1996).…”