Abandono do tratamento da tuberculose no Brasil, 2012-2018: tendência e distribuição espaço-temporal

Soeiro, Vanessa Moreira da Silva; Caldas, Arlene de Jesus Mendes; Ferreira, Thaís Furtado

doi:10.1590/1413-81232022273.45132020

Cited by 12 publications

(13 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Individuals with untreated TB, in addition to transmitting the bacillus, may have a clinical evolution of the disease to more severe forms. Those who abandon treatment may still have multidrug resistance to available drugs (SOEIRO, 2022). In the period studied, from 2017 to 2021, 55,900 cases of tuberculosis treatment abandonment were observed, distributed across the 5 Brazilian macro-regions.…”

Section: Resultsmentioning

confidence: 99%

The evolution of HIV/AIDS knowledge

Collela¹,

Navarro²,

Zandona³

et al. 2024

Eyes on Health Sciences

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

The evolution of HIV/AIDS knowledge

Collela¹,

Navarro²,

Zandona³

et al. 2024

Eyes on Health Sciences

View full text Add to dashboard Cite

show abstract

“…TB and COVID-19, two diseases with distinct histories, have notable similarities, such as their airborne transmission, the presence of key symptoms such as cough and fever, and their high potential to cause structural pulmonary sequelae, in addition to being affected by social stigma [ 31 ]. Currently, the COVID-19 pandemic has been identified as one of the main obstacles to the effectiveness of TB control measures on a global scale over the past 2 years [ 32 , 34 ].…”

Section: Discussionmentioning

confidence: 99%

Unsuccessful tuberculosis treatment outcomes across Brazil's geographical landscape before and during the COVID-19 pandemic: are we truly advancing toward the sustainable development/end TB goal?

Tavares,

Berra,

Alves

et al. 2024

Infect Dis Poverty

View full text Add to dashboard Cite

Background Tuberculosis is one of the most significant infectious diseases for global public health. The reallocation of healthcare resources and the restrictions imposed by the COVID-19 pandemic have hindered access to TB diagnosis and treatment. Increases in unfavorable outcomes of the disease have been observed in Brazil. The objective of this study was to analyze the spatial distribution of unfavorable TB treatment outcomes in Brazil before and during the pandemic. Methods An ecological study with spatial analysis was conducted with all 5569 municipalities in Brazil. All reported cases of tuberculosis between January 2010 and December 2021, as well as reported cases of COVID-19 from February 2020 to December 2021, were included. The outcomes studied encompass loss to follow-up, drug-resistant tuberculosis, and death. The Getis Ord GI* technique was employed to assess spatial association, and the Kernel density estimator was used to identify areas with concentrated increases or decreases in outcomes. Bivariate Local Moran's I was used to examine the spatial association between outcomes and COVID-19 incidence. The study was approved by the Research Ethics Committee of Ribeirão Preto Nursing School, University of São Paulo. Results There were 134,394 cases of loss to follow-up, 10,270 cases of drug resistance, and 37,863 deaths. Clusters of high and low values were identified for all three outcomes, indicating significant changes in the spatial distribution patterns. Increases in concentrations were observed for lost to follow-up cases in the Southeast, while reductions occurred in the Northeast, South, and Midwest. Drug-resistant tuberculosis experienced an increase in the Southern and Southeastern regions and a decrease in the Northeast and South. TB-related deaths showed notable concentrations in the Midwest, Northeast, South, and Southeast. There was an increase in high occurrence clusters for deaths after 2020 and 2021 in the Northeast. Conclusions The pandemic has brought additional challenges, emphasizing the importance of enhancing efforts and disease control strategies, prioritizing early identification, treatment adherence, and follow-up. This commitment is vital for achieving the goal of tuberculosis elimination.

show abstract

“…De acordo com levantamento feito em todos os estados, somente no Acre e no Piauí a proporção de interrupção do tratamento foi menor que 5,0% de 2012 até 2018. Esse indicador em Sergipe foi de 11,8%, índice semelhante ao identificado na presente pesquisa 47 . Essa realidade indica que, mesmo com a implementação de políticas públicas, como o TDO, a interrupção do tratamento e consequentemente a cura ainda necessitam de ações corretivas, pois as taxas de interrupção se refletem no aumento da transmissibilidade, dos custos de tratamento, da morbidade e da mortalidade, bem como da resistência medicamentosa.…”

Section: Discussionunclassified

Série temporal dos casos e dos desfechos do tratamento contra tuberculose em Sergipe, 2012–2021

Batista,

Santos,

Jesus

et al. 2023

Rev. bras. epidemiol.

View full text Add to dashboard Cite

RESUMO Objetivo: Os objetivos deste estudo são, no estado de Sergipe: (1) analisar a tendência temporal da tuberculose e os desfechos do tratamento; (2) identificar a existência de sazonalidade da tuberculose; (3) verificar a influência do teste rápido molecular (TRM-TB) na série temporal da tuberculose e seus desfechos de tratamento; e (4) verificar os desfechos do tratamento. Métodos: Estudo ecológico sobre tuberculose e três desfechos do tratamento (cura, interrupção do tratamento e óbito) extraídos do Datasus. Foram calculadas as taxas de incidência e de mortalidade para as ocorrências brutas de casos e as proporções de cura e interrupção do tratamento (%). A série temporal foi analisada pela regressão de Prais-Winsten no período de janeiro de 2012 a dezembro de 2021. Resultados: A taxa de incidência total foi de 36,35 casos por 100 mil habitantes, com aumento de 0,44% ao mês (IC95% 0,35; 0,54). A proporção de cura foi de 64,0%, com tendência estacionária (p>0,05). O percentual de interrupção do tratamento foi de 13,3%, com redução de 0,73% ao mês (IC95% −1,11; −0,34). A taxa de mortalidade total foi de 1,92 morte por100 mil habitantes, com tendência estacionária. Posteriormente à implementação do TRM-TB, a taxa de incidência cresceu 0,65% ao mês. A sazonalidade não foi identificada em nenhuma das análises realizadas (p>0,05). Conclusão: Cresceram as taxas de incidência, redução da interrupção do tratamento e mortalidade no estado de Sergipe. Não foi identificado sazonalidade. O teste rápido molecular apresentou efeito de crescimento na taxa de incidência.

show abstract

Abandono do tratamento da tuberculose no Brasil, 2012-2018: tendência e distribuição espaço-temporal

Cited by 12 publications

References 16 publications

The evolution of HIV/AIDS knowledge

The evolution of HIV/AIDS knowledge

Unsuccessful tuberculosis treatment outcomes across Brazil's geographical landscape before and during the COVID-19 pandemic: are we truly advancing toward the sustainable development/end TB goal?

Série temporal dos casos e dos desfechos do tratamento contra tuberculose em Sergipe, 2012–2021

Contact Info

Product

Resources

About