Resenhas

Green synthesis of glycerol 1,3-bromo- and iodohydrins under solvent-free conditions

“…The dichlorohydrins (DCH's) are low-cost glycerol derivatives with important industrial applications, being used mainly for the manufacture of epoxy resins, acting as a substrate and solvent during the process. The 1,3-diclorohydrin (1,3-DCH) is largely obtained from propene; however, sustainable synthesis in one step from glycerol using HCl catalyzed by acetic acid and Cl 2 at high temperatures are already consolidated (9)(10)(11)(12)(13)(14). On the other hand, the brominated and iodinated derivatives of glycerol are mainly applied as intermediates in fine chemistry, whereas they exhibit higher reactivity than DCHs.…”

“…In our continuing interest in adding value to glycerolsurpluses originated from biodiesel using sustainable and eco-friendly (8,9) routes, now we desire to describe the development of green processes for obtaining bromohydrins and iodohydrins from glycerol-biodiesel. Thus, the reactivity of metal halides in the presence or absence of additives (tetrabutylammonium bromide (TBAB)) and tetrabutylammonium iodide (TBAI) with glycerol-1,3-dichlorohydrin 1, in homogeneous medium solventless was investigated.…”

Morabia A. Enigmas of Health and Disease: How Epidemiology Helps Unravel Scientic Misteries. New York: Columbia University Press; 2014.

“…O enfoque é mais histórico do que de outros livros de epidemiologia próprios para ministrar cursos, não se constituindo em um livro didático. De fato, nesses capítulos específicos, o livro em muito se assemelha à obra de Ujvari e Adoni, de 2014, recentemente tema de resenha publicada 5 , com a diferença de que a obra de Morabia tem uma visão mais histórica de todo o processo e também pelo fato de que não está publicada em português. Além disso, o livro de Ujvari e Adoni se aventura mais sobre o que seria o futuro da Medicina, com um longo capítulo sobre genética.…”