Tooth biomineralization is a dynamic
and complicated process influenced
by local and systemic factors. Abnormal mineralization in teeth occurs
when factors related to physiologic mineralization are altered during
tooth formation and after tooth maturation, resulting in microscopic
and macroscopic manifestations. The present Review provides timely
information on the mechanisms and structural alterations of different
forms of pathological tooth mineralization. A comprehensive study
of these alterations benefits diagnosis and biomimetic treatment of
abnormal mineralization in patients.