Influence of nitric oxide in the improvement of muscle power

Abstract

OBJECTIVETo evaluate whether nitric oxide (NO) supplementa-tion is directly related to increased muscle power in response to strength exercise trainingMETHODSThe study included 36 individuals who underwent training for eight weeks (three times per week) with weights, who were randomly divided into two groups, both receiving the same training protocol, but one group used 3g of arginine, as a precursor of NO, and the other received placeboRESULTSThere was no significant difference between groups, only a significant difference for both groups between moments: before and after the training protocolCONCLUSIONOral administration of arginine asso-ciated with a training program did not increase the muscular power of individuals. Level of Evidence I, Study Type: Highquality randomized trial with statistically significant diffe-rence or no statistically significant difference but narrow confidence intervals.

Impact of Optimal Timing of Intake of Multi-Ingredient Performance Supplements on Sports Performance, Muscular Damage, and Hormonal Behavior across a Ten-Week Training Camp in Elite Cyclists: A Randomized Clinical Trial

“…It stimulates vasodilation by improving blood flow, is involved in skeletal-muscle energy metabolism via stimulating mitochondrial oxidation, and has restorative properties in EIMD [13,69]. Such properties attributed to NO could be responsible for increased sports performance [70]. Supplementation with L-Citrulline has a dual effect by simultaneously increasing plasma levels of L-Arginine and L-Citrulline [71].…”

A proprietary blend of Sphaeranthus indicus flower head and Mangifera indica bark extracts increases muscle strength and enhances endurance in young male volunteers: a randomized, double-blinded, placebo-controlled trial

“…Based on scientific understanding, we believe that the mode of action of this novel botanical formulation is unlike that of conventional NO boosters. The ergogenic benefits of these NO boosters, such as L-arginine, citrulline, or dietary nitrates, are transient ( 28 , 29 ). There is insufficient evidence supporting these NO boosters on eNOS activation and improved mitochondrial function.…”