Histomorphometric bone assessment in patients with fracture of the proximal end of the femur

Abstract

OBJECTIVE: To determine whether there is a difference on the bone architecture in patients with femoral neck fracture compared to patients with intertrochanteric fractures and assess the importance of aging on bone microarchitecture in patients with proximal femoral fracture. METHODS: Biopsy of the iliac crest was made in seventeen patients between 55 and 90 years old who were admitted to the emergency room with fractures of the proximal end of the femur. After a small fragment was removed, we made a histomorphometric analysis of it. RESULTS: There was no significant difference between patients with femoral neck fracture and trochanteric fracture in structural parameters, formation and resorption. Comparing age groups we also did not find any significant change between the groups in the parameters volume and trabecular separation. CONCLUSION: There are no difference in the morphometric parameters analyzed between the different types of fracture and age is not a significant factor in the alteration of these parameters. Level of Evidence II, Diagnostic Studies.

Impacto da sobrecarga de ferro no tecido hepático, miocárdico e ósseo de pacientes em hemodiálise

“…dose de 500 mg a cada 12h/12h por 3 dias, separados por 10 dias livres de medicamento -a biópsia foi realizada de 3 a 5 dias após o término do antibiótico. A biopsia óssea foi processada com técnica padronizada que permite analisar o tecido sem descalcificação prévia(64). A análise histomorfométrica foi realizada empregando-se método semi automatizado, com o software Osteomeasure…”