Synthesis and characterization of Fe3O4-NH2 and Fe3O4-NH2-chitosan nanoparticles

Abstract

Fe 3 O 4 nanoparticles were synthesized and functionalized with (3-aminopropyl) trimethoxysilane (APTMS) and chitosan, forming Fe 3 O 4 -NH 2 and Fe 3 O 4 -NH 2 -chitosan nanoparticles. The Fe 3 O 4 nanoparticles were synthesized by a co-precipitation method and functionalization was performed in further stages. The nanoparticles were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), zeta potential, and transmission electron microscopy (TEM). The results of XRD showed that magnetite did not experience an oxidation reaction. The functionalization of the surface of Fe 3 O 4 nanoparticles was confirmed by FTIR and zeta potential measurements. The TEM results showed a thin layer around Fe 3 O 4 nanoparticles due to the functionalization with the APTMS. The later functionalization by chitosan contributed to the agglomeration of nanoparticles. Functionalization provided the nanoparticles better colloidal stability mainly for a pH below 7 and this improvement was related to the protection and new functional groups from the APTMS and chitosan.

The Effect of EDTA Functionalization on Fe3O4 Thermal Behavior

“…This result corroborates the stabilization of Fe 3 O 4 nanoparticles, which are less susceptible to oxidation when functionalized with EDTA and corroborate the previous result obtained by other techniques for this system 23 . In addition, it also supports the stabilization of Fe 3 O 4 nanoparticles by the coprecipitation method with organic molecules, such as also observed when used chitosan 17 .…”

“…The surface functionalization of nanoparticles can introduce new functions to nanoparticles, as it can change the chemical and physical properties. In the case of Fe 3 O 4 nanoparticles, it appears that the functionalization can improve the colloidal stability 1,2,[17][18][19][20][21][22][23] , increase the chemical and thermal stability against the oxidation reaction 23 , but depending on the functionalizing agent it can decrease the magnetic property [24][25][26] The oxidation reaction of the Fe 3 O 4 nanoparticles is one of the factors that contributes to the decrease in the magnetic properties. In addition to these functions mentioned above, Marcos-Hernández et al 27 studied nano-Fe 3 O 4 electrodes with the aim of electrochemical reduction of nitrate.…”

Toxicological effects of pure and amine-functionalized ZnO nanorods on Daphnia magna and Lactuca sativa

“…34 The modification of NM surfaces by APTMS provides potential for several applications such as environmental remediation and biomedicine, among others, 34 increasing NM reactivity with other chemical structures, thus generating multifunctional NMs. 35 APTMS is widely used in drug delivery studies [36][37][38] due to its good slow drug release results, optimizing compound absorption and reducing its toxicity due to its controlled release.…”