2022
DOI: 10.1590/0104-1428.210018
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Scaffold based on castor oil as an osteoconductive matrix in bone repair: biocompatibility analysis

Abstract: To analyze the biocompatibility of the scaffold produced from a natural polymer derived from castor oil through hemolytic activity and antimicrobial activity, to enable the clinical application. Three in vitro tests were performed: Hemolytic activity test -Polymer partially dissolved in contact with blood agar; Hemolytic activity test in sheep's blood -Polymer extract with red blood cells solution; Antimicrobial activity test -Solid polymer in direct contact with E. Coli and S. Aureus. For hemolytic tests, non… Show more

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Cited by 2 publications
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“…In this sense, biopolymers of plant origin have been used for developing products to the biomedical field, including polyurethane [3][4][5][6][7][8] . Polyurethane from castor oil is a compound that consists of a prepolymer and a polyol extracted from the seed oil of the Ricinus communis plant, which does not exude toxic vapors and is a biocompatible material [9,10] .…”
Section: Introductionmentioning
confidence: 99%
“…In this sense, biopolymers of plant origin have been used for developing products to the biomedical field, including polyurethane [3][4][5][6][7][8] . Polyurethane from castor oil is a compound that consists of a prepolymer and a polyol extracted from the seed oil of the Ricinus communis plant, which does not exude toxic vapors and is a biocompatible material [9,10] .…”
Section: Introductionmentioning
confidence: 99%